Sjögren's syndrome (SjS) is an autoimmune disease characterized by the triad of sicca
symptoms, fatigue and pain. This diagnosis is usually made in women at the average age of …

Sjogren disease (SD) is a chronic, systemic autoimmune disease marked by
immunemediated exocrine gland destruction that affects approximately 4 million individuals …

Findings from large cohort studies provide a framework for the future development of
diagnostic criteria for cSS. Such criteria should incorporate objective measures that are …

Approximately 1% of all patients with Sjögren's syndrome (SS) are children. Unlike the adult
form, in which sicca syndrome is the main presentation, in children, the most common …

Summary Background Childhood Sjögren's disease is a rare, underdiagnosed, and poorly-
understood condition. By integrating machine learning models on a paediatric cohort in the …

Childhood Sjögren's disease represents critically unmet medical needs due to a complete
lack of immunological and molecular characterizations. This study presents key immune cell …

Introduction The initial presentations of childhood-onset primary Sjögren's syndrome (C-
pSS) vary, making diagnosis challenging. We aimed to improve the diagnosis and …

Objectives To describe characteristic features in children with recurrent or persistent salivary
gland enlargement and to propose a diagnostic algorithm with specific consideration for …

Background Sjogren's Syndrome (SS) is characterized by xeropthalmia and/or xerostomia.
Treating the associated salivary gland hypofunction has been challenging to the clinicians …

Timely referral to an ophthalmologist can address perceived feasibility issues with respect to
ocular features in jSjD. Management of keratoconjunctivitis sicca in jSjD includes improving …