Abstract Background Patients with Parkinson's disease experience visual symptoms,
partially originating from retinal changes. Since 2011, multiple case-control studies using …

Alzheimer's disease (AD) is a neurodegenerative condition that primarily affects brain tissue.
Because the retina and brain share the same embryonic origin, visual deficits have been …

Background Several retinal pathologies exhibit both inflammation and breakdown of the
inner blood-retinal barrier (iBRB) resulting in vascular permeability, suggesting that …

Amyloid beta (Aβ) deposits in the retina of the Alzheimer's disease (AD) eye may provide a
useful diagnostic biomarker for AD. This study focused on the relationship of Aβ with …

Background The identification of endogenous signals that lead to microglial activation is a
key step in understanding neuroinflammatory cascades. As ATP release accompanies …

As the mammalian central nervous system matures, its regenerative ability decreases,
leading to incomplete or non‐recovery from the neurodegenerative diseases and central …

Retina and optic nerve are sites of extra-cerebral manifestations of Alzheimer's Disease
(AD). Amyloid-β (Aβ) plaques and neurofibrillary tangles of hyperphosphorylated tau protein …

Primary open-angle glaucoma is currently characterized by a pattern of progressive retinal
ganglion cell loss that stems from a complex underlying pathophysiology that remains poorly …

Most neurodegenerative disorders, including the two most common, Alzheimer's disease
(AD) and Parkinson's disease (AD), course with activation of microglia, the resident innate …

Recent studies have linked carbonyl stress to many physiological processes. Increase in the
levels of carbonyl compounds, derived from both endogenous and exogenous sources, is …