Zinc (Zn2+) functions as a signalling molecule in the nervous system and modulates many
ionic channels. In this study, we have explored the effects of Zn2+ on recombinant T‐type …

Chloroquine and hydroxychloroquine have been proposed recently as therapy for SARS-
CoV-2-infected patients, but during 3 months of extensive use concerns were raised related …

Zinc ion (Zn 2+) is an endogenous allosteric modulator that regulates the activity of a wide
variety of ion channels in a reversible and concentration-dependent fashion. Here we used …

In this review, we focus on two attributes of P2X receptor channel function, one essential and
one novel. First, we propose that P2X receptors are extracellular sensors as well as …

Inhibition of epithelial Na+ channel (ENaC) activity by high concentrations of extracellular
Na+ is referred to as Na+ self-inhibition. We investigated the effects of external Zn 2+ on …

Abstract Background Lung epithelial Na+ channels (ENaC) are regulated by cell Ca 2+
signal, which may contribute to calcium antagonist-induced noncardiogenic lung edema …

Cellular asymmetry is an important element of efficiency in the compartmentalization of
intracellular chemical reactions that ensure efficient tissue function. Improving the current 3D …

To better understand how renal Na+ reabsorption is altered by heavy metal poisoning, we
examined the effects of several divalent heavy metal ions (Zn2+, Ni2+, Cu2+, Pb2+, Cd2+ …

The typical response to the lowering of plasma Na+ concentration and blood pressure in our
body involves the release of aldosterone from the adrenal glands, which triggers the …

ELECTROPHYSIOLOGY AND PHARMACOLOGY STUDY OF A HUMAN NEUROBLASTOMA
CELL LINE Page 1 Romanian Reports in Physics, Vol. 67, No. 2, P. 439–451, 2015 …