Nonalcoholic fatty liver disease (NAFLD) is a common, progressive liver disease that affects
up to one-quarter of the adult population worldwide. The clinical and economic burden of …

The mechanisms of how obesity contributes to the development of cardio-metabolic
diseases are not entirely understood. Obesity is frequently associated with adipose tissue …

Circulating proteomic signatures of age are closely associated with aging and age-related
diseases; however, the utility of changes in secreted proteins in identifying therapeutic …

The burden of nonalcoholic fatty liver disease (NAFLD) is rising globally. Cardiovascular
disease is the leading cause of death in patients with NAFLD. Nearly half of individuals with …

The term diabetic cardiomyopathy (DCM) labels an abnormal cardiac structure and
performance due to intrinsic heart muscle malfunction, independently of other vascular co …

Aims Takotsubo syndrome (TTS) is associated with a substantial rate of adverse events. We
sought to design a machine learning (ML)‐based model to predict the risk of in‐hospital …

Hypertension is an important risk factor for cardiovascular morbidity and mortality and for
events such as myocardial infarction, stroke, heart failure and chronic kidney disease and is …

Background. Cardiovascular disease (CVD) is the combination of coronary heart disease,
myocardial infarction, rheumatic heart disease, and peripheral vascular disease of the heart …

Cardiovascular diseases are a major cause of disability and they are currently responsible
for a significant number of deaths in a large percentage of the world population. A large …

Aims Myocardial infarction (MI) is the most common cause of heart failure (HF) worldwide. G
protein-coupled receptor kinase 5 (GRK5) is upregulated in failing human myocardium and …