The impact of ultraviolet radiation on skin photoaging—review of in vitro studies

KJ Gromkowska‐Kępka… - Journal of cosmetic …, 2021 - Wiley Online Library
Background Photoaging, ultra violet (UV) induced skin aging is a gradual process that
depends on the time and intensity of solar radiation. Aim The aim of this paper was to review …

[HTML][HTML] Sunlight damage to cellular DNA: Focus on oxidatively generated lesions

AP Schuch, NC Moreno, NJ Schuch… - Free Radical Biology …, 2017 - Elsevier
The routine and often unavoidable exposure to solar ultraviolet (UV) radiation makes it one
of the most significant environmental DNA-damaging agents to which humans are exposed …

Effects of air pollution on cellular senescence and skin aging

I Martic, P Jansen-Dürr, M Cavinato - Cells, 2022 - mdpi.com
The human skin is exposed daily to different environmental factors such as air pollutants and
ultraviolet (UV) light. Air pollution is considered a harmful environmental risk to human skin …

Adaptive homeostasis and the free radical theory of ageing

LCD Pomatto, KJA Davies - Free Radical Biology and Medicine, 2018 - Elsevier
Abstract The Free Radical Theory of Ageing, was first proposed by Denham Harman in the
mid-1950's, based largely on work conducted by Rebeca Gerschman and Daniel Gilbert. At …

Plant extracts and natural compounds used against UVB-induced photoaging

M Cavinato, B Waltenberger, G Baraldo, CVC Grade… - Biogerontology, 2017 - Springer
Skin is continuously exposed to a variety of environmental stresses, including ultraviolet
(UV) radiation. UVB is an inherent component of sunlight that crosses the epidermis and …

Molecular mechanisms of UVB-induced senescence of dermal fibroblasts and its relevance for photoaging of the human skin

M Cavinato, P Jansen-Dürr - Experimental gerontology, 2017 - Elsevier
Due to its ability to cross the epidermis and reach the upper dermis where it causes
cumulative DNA damage and increased oxidative stress, UVB is considered the most …

Aging in the dermis: Fibroblast senescence and its significance

J Zhang, H Yu, MQ Man, L Hu - Aging Cell, 2024 - Wiley Online Library
Skin aging is characterized by changes in its structural, cellular, and molecular components
in both the epidermis and dermis. Dermal aging is distinguished by reduced dermal …

The role of microRNAs in organismal and skin aging

M Gerasymchuk, V Cherkasova, O Kovalchuk… - International journal of …, 2020 - mdpi.com
The aging process starts directly after birth and lasts for the entire lifespan; it manifests itself
with a decline in an organism's ability to adapt and is linked to the development of age …

Autophagy plays an essential role in ultraviolet radiation-driven skin photoaging

J Ma, Y Teng, Y Huang, X Tao, Y Fan - Frontiers in Pharmacology, 2022 - frontiersin.org
Photoaging is characterized by a chronic inflammatory response to UV light. One of the most
prominent features of cutaneous photoaging is wrinkling, which is due primarily to a loss of …

Autophagy: multiple mechanisms to protect skin from ultraviolet radiation‐driven photoaging

M Wang, P Charareh, X Lei… - Oxidative Medicine and …, 2019 - Wiley Online Library
Autophagy is an essential cellular process that maintains balanced cell life. Restriction in
autophagy may induce degenerative changes in humans. Natural or pathological aging of …