Relationship between oxidative stress, circadian rhythms, and AMD

ML Fanjul-Moles… - Oxidative Medicine and …, 2016 - Wiley Online Library
This work reviews concepts regarding oxidative stress and the mechanisms by which
endogenous and exogenous factors produce reactive oxygen species (ROS). It also surveys …

Pre-mRNA processing factors and retinitis pigmentosa: RNA splicing and beyond

C Yang, M Georgiou, R Atkinson, J Collin… - Frontiers in cell and …, 2021 - frontiersin.org
Retinitis pigmentosa (RP) is the most common inherited retinal disease characterized by
progressive degeneration of photoreceptors and/or retinal pigment epithelium that …

Damage of photoreceptor-derived cells in culture induced by light emitting diode-derived blue light

Y Kuse, K Ogawa, K Tsuruma, M Shimazawa… - Scientific reports, 2014 - nature.com
Our eyes are increasingly exposed to light from the emitting diode (LED) light of video
display terminals (VDT) which contain much blue light. VDTs are equipped with televisions …

Ultraviolet to blue blocking and wavelength convertible films using carbon dots for interrupting eye damage caused by general lighting

SJ Park, HK Yang, BK Moon - Nano Energy, 2019 - Elsevier
Our eyes are regularly exposed to ultraviolet (UV) and blue light emitting diode (LED) light-
based devices. However, the blue light induces macular degeneration, optic nerve crush …

Stress reaction in outer segments of photoreceptors after blue light irradiation

C Roehlecke, U Schumann, M Ader, C Brunssen… - PLoS …, 2013 - journals.plos.org
The retina is prone to oxidative stress from many factors which are also involved in the
pathogenesis of degenerative diseases. In this study, we used the application of blue light …

The Flavone Cirsiliol from Salvia x jamensis Binds the F1 Moiety of ATP Synthase, Modulating Free Radical Production

L Carlini, G Tancreda, V Iobbi, F Caicci, S Bruno… - Cells, 2022 - mdpi.com
Several studies have shown that mammalian retinal rod outer segments (OS) are peculiar
structures devoid of mitochondria, characterized by ectopic expression of the molecular …

Influence of light emitting diode-derived blue light overexposure on mouse ocular surface

HS Lee, L Cui, Y Li, JS Choi, JH Choi, Z Li, GE Kim… - PLoS …, 2016 - journals.plos.org
Purpose To investigate the influence of overexposure to light emitting diode (LED)-derived
light with various wavelengths on mouse ocular surface. Methods LEDs with various …

Photobiomodulation mediates neuroprotection against blue light induced retinal photoreceptor degeneration

N Heinig, U Schumann, D Calzia, I Panfoli… - International journal of …, 2020 - mdpi.com
Potent neuroprotective effects of photobiomodulation with 670 nm red light (RL) have been
demonstrated in several models of retinal disease. RL improves mitochondrial metabolism …

Three-dimensional automated reporter quantification (3D-ARQ) technology enables quantitative screening in retinal organoids

MN Vergara, M Flores-Bellver… - …, 2017 - journals.biologists.com
The advent of stem cell-derived retinal organoids has brought forth unprecedented
opportunities for developmental and physiological studies, while presenting new therapeutic …

Antioxidants for the treatment of retinal disease: summary of recent evidence

P Wang, EK Chin, D Almeida - Clinical Ophthalmology, 2021 - Taylor & Francis
Retinal tissue is prone to oxidant burden and oxidative stress secondary to the generation of
reactive oxygen species from high metabolic demand. The formation of reactive oxygen …