The ability of skin to act as a barrier is primarily determined by cells that maintain the
continuity and integrity of skin and restore it after injury. Cutaneous wound healing in adult …

Osteopontin (OPN) is a highly phosphorylated sialoprotein that is a prominent component of
the mineralized extracellular matrices of bones and teeth. OPN is characterized by the …

The glycoprotein osteopontin (OPN) possesses multiple functions in health and disease. To
this end, osteopontin has beneficial roles in wound healing, bone homeostasis, and …

Numerous components and pathways are involved in the complex interplay between cancer
cells and their environment. The family of glycophosphoproteins comprising osteopontin …

The extracellular matrix (ECM) of bone and dentin contains several non-collagenous
proteins. One category of non-collagenous protein is termed the SIBLING (S mall I ntegrin-B …

Abstract Osteopontin (OPN), a chemokine-like protein, plays a crucial role in the proliferation
and metastasis of various cancers. However, how tumor stroma modulates the expression of …

Since its first identification as a transformation-associated protein, osteopontin (OPN) has
been recognised as important in the processes of tumorigenicity and metastasis. Here, we …

Osteopontin (OPN) is a glyco-phosphoprotein that is expressed and secreted by numerous
human cancers. OPN functions in cell adhesion, chemotaxis, macrophage-directed …

Osteopontin (OPN) is an acidic member of the small integrin-binding ligand N-linked
glycoprotein (SIBLING) family of extracellular matrix proteins/cytokines that undergoes …

Osteopontin (OPN), a multifunctional protein, has emerged as a potentially valuable
biomarker for diagnosing and treating cancers. Recent research focuses on its involvement …