Inflammasomes are multimolecular complexes with potent inflammatory activity. As such,
their activity is tightly regulated at the transcriptional and post-transcriptional levels. In this …

Arrhythmogenic cardiomyopathy (ACM) is a familial, nonischemic heart disease typically
inherited via an autosomal dominant pattern (Nava et al.,[1]; Wlodarska et al.,[2]). Often …

A severe complication of hematopoietic stem cell transplantation is graft-versus-host disease
(GvHD), a reaction that occurs following the transfer of donor immune cells (the graft) into an …

Back and neck pain are significant healthcare burdens that are commonly associated with
pathologies of the intervertebral disc (IVD). The poor understanding of the cellular …

The concept of non-self recognition through germ-line encoded pattern recognition
receptors (PRRs) has been well-established for professional innate immune cells. However …

Background The immune system plays a vital role in the pathophysiology of acute
myocardial infarction (AMI). However, the exact immune related mechanism is still unclear …

The pathogenesis of bronchopulmonary dysplasia (BPD), involves inflammatory,
mechanisms that are not fully characterized. Here we report that overexpression of CC …

Postpartum uterine infection in dairy cows is commonly caused by pathogenic bacteria such
as Escherichia coli (E. coli). Progesterone elicits immunosuppressive function within bovine …

Stress-induced immunosuppression is a serious problem affecting the production value of
poultry, but its specific molecular mechanism has not yet been elucidated. We selected 7 …

Inflammation is one of the vital mechanisms through which the immune system responds to
harmful stimuli. During inflammation, proinflammatory and anti-inflammatory cytokines …