Neonatal hypoxia ischaemia: mechanisms, models, and therapeutic challenges

LJ Millar, L Shi, A Hoerder-Suabedissen… - Frontiers in cellular …, 2017 - frontiersin.org
Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …

Perinatal brain injury and inflammation: lessons from experimental murine models

A Leavy, EM Jimenez Mateos - Cells, 2020 - mdpi.com
Perinatal brain injury or neonatal encephalopathy (NE) is a state of disturbed neurological
function in neonates, caused by a number of different aetiologies. The most prominent cause …

Cortical somatosensory reorganization in children with spastic cerebral palsy: a multimodal neuroimaging study

C Papadelis, B Ahtam, M Nazarova, D Nimec… - Frontiers in human …, 2014 - frontiersin.org
Although cerebral palsy (CP) is among the most common causes of physical disability in
early childhood, we know little about the functional and structural changes of this disorder in …

Developmental changes in somatosensory processing in cerebral palsy and healthy individuals

I Riquelme, P Montoya - Clinical Neurophysiology, 2010 - Elsevier
OBJECTIVE: Cerebral palsy (CP) is a motor disorder that causes physical disability in
human development. Recent work has shown that somatosensory deficits are a serious …

[HTML][HTML] Reorganization of the somatosensory cortex in hemiplegic cerebral palsy associated with impaired sensory tracts

C Papadelis, EE Butler, M Rubenstein, L Sun… - NeuroImage: Clinical, 2018 - Elsevier
Functional neuroimaging studies argue that sensory deficits in hemiplegic cerebral palsy
(HCP) are related to deviant somatosensory processing in the ipsilesional primary …

Neonatal kaempferol exposure attenuates impact of cerebral palsy model on neuromotor development, cell proliferation, microglia activation, and antioxidant enzyme …

DB Visco, R Manhães-de-Castro… - Nutritional …, 2024 - Taylor & Francis
Objectives This study aims to assess the effect of neonatal treatment with kaempferol on
neuromotor development, proliferation of neural precursor cells, the microglia profile, and …

Botulinum toxin assessment, intervention and follow‐up for paediatric upper limb hypertonicity: international consensus statement

D Fehlings, I Novak, S Berweck, B Hoare… - European Journal of …, 2010 - Wiley Online Library
The primary objective of this paper was to evaluate the published evidence of efficacy and
safety of botulinum neurotoxin (BoNT) injections in paediatric upper limb hypertonia (PULH) …

Resveratrol reduces neuroinflammation and hippocampal microglia activation and protects against impairment of memory and anxiety-like behavior in experimental …

CMSS Calado, R Manhães-de-Castro… - Molecular …, 2024 - Springer
Cerebral palsy (CP) is a neurodevelopmental disorder characterized by motor and postural
impairments. However, early brain injury can promote deleterious effects on the …

Fibroblast growth factor 19 as a countermeasure to muscle and locomotion dysfunctions in experimental cerebral palsy

SC Pereira, B Benoit… - Journal of Cachexia …, 2021 - Wiley Online Library
Background Cerebral palsy (CP) associates cerebral function damages with strong
locomotor defects and premature sarcopenia. We previously showed that fibroblast growth …

Prenatal ischemia deteriorates white matter, brain organization, and function: implications for prematurity and cerebral palsy

JO Coq, M Delcour, VS Massicotte… - … Medicine & Child …, 2016 - Wiley Online Library
Cerebral palsy (CP) describes a group of neurodevelopmental disorders of posture and
movement that are frequently associated with sensory, behavioral, and cognitive …