Polysaccharides have attracted considerable attention in a broad range of applications in
recent years, which is due to their remarkable features such as biocompatibility …

Among the various dosage forms, oral medicine has extensive benefits including ease of
administration and patients' compliance, over injectable, suppositories, ocular and nasal …

With the rise in diabetes mellitus cases worldwide and lack of patient adherence to glycemia
management using injectable insulin, there is an urgent need for the development of …

Chitosan is a cationic polysaccharide that is usually obtained by alkaline deacetylation of
chitin poly (N-acetylglucosamine). It is biocompatible, biodegradable, mucoadhesive, and …

Abstract Encapsulation in polymer NPs (NPs) is a well-recognized way to improve the oral
bioavailability of hydrophobic and hydrophilic compounds by enhancing their solubility in …

Insulin is essential for type 1 and advanced type 2 diabetics to maintain blood glucose levels
and prolong lives. The traditional administration requires frequent subcutaneous insulin …

First-generation nanoparticles (NPs) have been clinically translated as pharmaceutical drug
delivery carriers for their ability to improve on drug tolerability, circulation half-life, and …

Chitosan (CS) is one of the most successfully developed biodegradable polymers. Among
the numerous polymers developed to formulate polymeric nanoparticles, CS has fascinated …

Chitosan (CS), a cationic polysaccharide, is widely regarded as a safe and efficient intestinal
absorption enhancer of therapeutic macromolecules, owing to its inherent mucoadhesive …

Nanoparticles have demonstrated significant advancements in potential oral delivery of
insulin. In this publication, we review the current status of polymeric, inorganic and solid-lipid …