Nicotinamide mononucleotide: a promising molecule for therapy of diverse diseases by targeting NAD+ metabolism

W Hong, F Mo, Z Zhang, M Huang… - Frontiers in cell and …, 2020 - frontiersin.org
NAD+, a co-enzyme involved in a great deal of biochemical reactions, has been found to be
a network node of diverse biological processes. In mammalian cells, NAD+ is synthetized …

[HTML][HTML] Role and Potential Mechanisms of Nicotinamide Mononucleotide in Aging

SU Rahman, A Qadeer, Z Wu - Aging and Disease, 2024 - ncbi.nlm.nih.gov
Nicotinamide adenine dinucleotide (NAD+) has recently attracted much attention due to its
role in aging and lifespan extension. NAD+ directly and indirectly affects many cellular …

NMN sensor cocktail: selective sensing of nicotinamide mononucleotide over citric acid

HG Lee, NK Hong, YT Chang - Chemical Communications, 2023 - pubs.rsc.org
The fluorescent probe pair, NBD-B2 and Styryl-51F, selectively detects NMN over citric acid.
NBD-B2 exhibits increased fluorescence, while Styryl-51F shows decreased fluorescence …

Parental high-fat high-sugar diet intake programming inflammatory and oxidative parameters of reproductive health in male offspring

MN Sertorio, H César, EA de Souza… - Frontiers in Cell and …, 2022 - frontiersin.org
Parental nutrition can impact the health of future generations, programming the offspring for
the development of diseases. The developing germ cells of the offspring could be damaged …

Maternal high-fat or low-protein diets promote autism-related behavior and altered social behavior within groups in offspring male mice

N Zilkha, SG Chuartzman, R Fishman, S Ben-Dor… - Scientific Reports, 2024 - nature.com
Maternal malnutrition has been associated with neurodevelopmental deficits and long-term
implications on the offspring's health and behavior. Here, we investigated the effects of …

[HTML][HTML] Pharmacology and potential implications of nicotinamide adenine dinucleotide precursors

J She, R Sheng, ZH Qin - Aging and disease, 2021 - ncbi.nlm.nih.gov
Coenzyme I (nicotinamide adenine dinucleotide, NAD+/NADH) and coenzyme II
(nicotinamide adenine dinucleotide phosphate, NADP+/NADPH) are involved in various …

Human sperm functioning is related to the aquaporin-mediated water and hydrogen peroxide transport regulation

G Pellavio, U Laforenza - Biochimie, 2021 - Elsevier
Aquaporins (AQPs) are transmembrane water channels and some of them are permeable in
addition to water to other small solutes including hydrogen peroxide. The sperm cells of …

Complementary yet divergent effects of exercise and an exercise mimetic on microbiome in high-fat diet-induced obesity

J Yu, NA Youngson, DR Laybutt… - Physiological …, 2024 - journals.physiology.org
Exercise is beneficial for obesity, partially through increased mitochondrial activity and
raised nicotinamide adenine dinucleotide (NAD), a coenzyme critical for mitochondrial …

3D Printed Microneedles for the Transdermal Delivery of NAD+ Precursor: Toward Personalization of Skin Delivery

M Ali, S Namjoshi, K Phan, X Wu… - ACS Biomaterials …, 2024 - ACS Publications
3D printing of microneedles (μNDs) for transdermal therapy has the potential to enable
patient personalization based on the target disease, site of application, and dosage …

Association of pre-pregnancy body mass index and gestational weight gain with neonatal anogenital distance in a Chinese birth cohort

Z Wang, J Niu, H Ji, M Miao, L Yang, X Chen, X Li… - Reproductive …, 2022 - Springer
Background This study aimed to investigate the associations of pre-pregnancy body mass
index (BMI) and gestational weight gain (GWG) with anogenital distance (AGD) among …