Role of proteases in chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) is generally associated with progressive
destruction of airways and lung parenchyma. Various factors play an important role in the …
destruction of airways and lung parenchyma. Various factors play an important role in the …
Biological and genetic mechanisms of COPD, its diagnosis, treatment, and relationship with lung cancer
KH Czarnecka-Chrebelska, D Mukherjee… - Biomedicines, 2023 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is one of the most prevalent chronic adult
diseases, with significant worldwide morbidity and mortality. Although long-term tobacco …
diseases, with significant worldwide morbidity and mortality. Although long-term tobacco …
Alantolactone suppresses inflammation, apoptosis and oxidative stress in cigarette smoke-induced human bronchial epithelial cells through activation of Nrf2/HO-1 …
X Dang, B He, Q Ning, Y Liu, J Guo, G Niu… - Respiratory Research, 2020 - Springer
Background It is well established that airway remodeling and inflammation are
characteristics for chronic obstructive pulmonary disease (COPD). Moreover, cigarette …
characteristics for chronic obstructive pulmonary disease (COPD). Moreover, cigarette …
Human mesenchymal stromal cells exert HGF dependent cytoprotective effects in a human relevant pre-clinical model of COPD
Bone-marrow derived mesenchymal stromal cells (MSCs) have potent immunomodulatory
and tissue reparative properties, which may be beneficial in the treatment of inflammatory …
and tissue reparative properties, which may be beneficial in the treatment of inflammatory …
miRNA‐206 regulates human pulmonary microvascular endothelial cell apoptosis via targeting in chronic obstructive pulmonary disease
Y Sun, N An, J Li, J Xia, Y Tian, P Zhao… - Journal of cellular …, 2019 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is a leading cause of death due to tis high
morbidity and mortality. microRNAs have emerged as new biomarkers for the prognosis and …
morbidity and mortality. microRNAs have emerged as new biomarkers for the prognosis and …
Proteases and their inhibitors in chronic obstructive pulmonary disease
In the context of respiratory disease, chronic obstructive pulmonary disease (COPD) is the
leading cause of mortality worldwide. Despite much development in the area of drug …
leading cause of mortality worldwide. Despite much development in the area of drug …
Melatonin protects against COPD by attenuating apoptosis and endoplasmic reticulum stress via upregulating SIRT1 expression in rats
B He, W Zhang, J Qiao, Z Peng… - Canadian Journal of …, 2019 - cdnsciencepub.com
The apoptosis of bronchial and alveolar epithelial cells plays a key role in chronic
obstructive pulmonary disease (COPD). The endoplasmic reticulum (ER) stress induced by …
obstructive pulmonary disease (COPD). The endoplasmic reticulum (ER) stress induced by …
Airway epithelial cells exposed to wildfire smoke extract exhibit dysregulated autophagy and barrier dysfunction consistent with COPD
Background Individuals with respiratory disease are being increasingly exposed to wildfire
smoke as populations encroach further into forested regions and climate change continues …
smoke as populations encroach further into forested regions and climate change continues …
The role of oxidised self-lipids and alveolar macrophage CD1b expression in COPD
MP Ween, JB White, HB Tran, V Mukaro, C Jones… - Scientific reports, 2021 - nature.com
In chronic obstructive pulmonary disease (COPD) apoptotic bronchial epithelial cells are
increased, and their phagocytosis by alveolar macrophages (AM) is decreased alongside …
increased, and their phagocytosis by alveolar macrophages (AM) is decreased alongside …
Complement component 3 protects human bronchial epithelial cells from cigarette smoke-induced oxidative stress and prevents incessant apoptosis
Y Pei, J Zhang, J Qu, Y Rao, D Li, X Gai… - Frontiers in …, 2022 - frontiersin.org
The complement component 3 (C3) is a pivotal element of the complement system and plays
an important role in innate immunity. A previous study showed that intracellular C3 was …
an important role in innate immunity. A previous study showed that intracellular C3 was …