Lipids represent the most abundant molecular type in the brain, with a fat content of∼ 60%
of the dry brain weight in humans. Despite this fact, little attention has been paid to …

The chemical synapse is the principal form of contact between neurons of the central
nervous system. These synapses are typically configured as presynaptic axon terminations …

Norepinephrine (NE) is synthesized in the Locus Coeruleus (LC) of the brainstem, from
where it is released by axonal varicosities throughout the brain via volume transmission. A …

Synapses are key structures in neural networks, and are involved in learning and memory in
the central nervous system. Investigating synaptogenesis and synaptic aging is important in …

Stress augments the rewarding memory of cocaine, which plays a critical role in inducing
cocaine craving. However, the neurobiological mechanisms underlying the enhancing effect …

Early odor preference learning in rodents occurs within a sensitive period [≤ postnatal day
(P) 10–12], during which pups show a heightened ability to form an odor preference when a …

Whereas activation of α 1-adrenoceptors (α 1-ARs) modulates glutamatergic transmission,
the roles of α 1-ARs in GABAergic transmission in the medial prefrontal cortex (mPFC) are …

Orexin is a neuropeptide restrictedly synthesized in the hypothalamus, but extensively
modulates the whole brain region activity including prefrontal cortex (PFC), and involved in …

Aging causes morphological and functional changes in the cerebellum. This work aimed to
demonstrate the implication of JAK1/STAT3/SOCS3 on aging–induced changes of rat …

Key points The effects of noradrenaline on excitatory synaptic transmission to regular
spiking (excitatory) cells as well as regular spiking non‐pyramidal and fast spiking (both …