Leishmaniasis is one of the most important tropical neglected diseases according to the
World Health Organization. Even after more than a century, we still have few drugs for the …

Leishmaniasis is regarded as a neglected tropical disease by World Health Organization
(WHO) and is ranked next to malaria as the deadliest protozoan disease. The primary …

Leishmaniasis is a complex protozoan infectious disease and, associated with malnutrition,
poor health services and unavailability of prophylactic control measures, neglected …

Neglected tropical diseases continue to create high levels of morbidity and mortality in a
sizeable fraction of the world's population, despite ongoing research into new treatments …

The repurposing strategy was applied herein to evaluate the effects of lopinavir, an aspartic
protease inhibitor currently used in the treatment of HIV-infected individuals, on the globally …

Leishmaniasis is a tropical disease caused by a protozoan parasite Leishmania that is
transmitted via infected female sandflies. At present, leishmaniasis treatment mainly counts …

The recent outlook of leishmaniasis as a global public health concern coupled with the
reportage of resistance and lack of efficacy of most antileishmanial drugs calls for a …

Chagas disease and leishmaniasis are both neglected tropical diseases that affect millions
of people around the world. Leishmaniasis is currently the second most widespread vector …

Leishmaniasis is a public health disease that requires the development of more effective
treatments and the identification of novel molecular targets. Since blocking the PI3K/AKT …

It is reported that the traditional scheme of finding and developing a new drug and
conducting the whole complex of preclinical studies requires several thousand chemical …