Ischemic stroke leads to high disability and mortality. The limited delivery efficiency of most
therapeutic substances is a major challenge for effective treatment of ischemic stroke …

Brain injuries affect a large patient population with major physical and emotional suffering
for patients and their relatives; at a significant cost to the society. Effective diagnostic and …

Overactive inflammatory response and excessive oxidative stress are the main
pathophysiological culprits for cerebral ischemia/reperfusion injury (IRI) that arouse …

Ischemic stroke represents one of the most prevalent pathologies in humans and is a
leading cause of death and disability. Anti-thrombolytic therapy with tissue plasminogen …

Ischemic stroke, a prominent cause of mortality and disability, is a combination of neuronal
and vascular disorders. Reperfusion techniques, such as administration of tissue …

Purpose We designed formulations based on minoxidil (MXD) nanoparticles (N-MXD) and
examined whether N-MXD can increase drug delivery into the follicles. In addition, we …

The aim of this work was to systematically study the effect of freeze-drying of bottom-up
processed cilostazol nanosuspension on the particle size after redispersion. Several …

Stroke represents the second leading cause of mortality and morbidity worldwide. Ischemic
strokes are the most prevalent type of stroke, and they are characterized by a series of …

The purpose of the present study was to evaluate the neuroprotective efficacy of optimized
thymoquinone loaded PLGA‐chitosan nanoparticles delivered via nose to brain route in the …

Ischemic stroke is caused by cerebrovascular stenosis or occlusion. Excessive reactive
oxygen species (ROS) are the focus‐triggering factor of irreversible injury in ischemic …