Chemerin–exploring a versatile adipokine
TF Fischer, AG Beck-Sickinger - Biological Chemistry, 2022 - degruyter.com
Chemerin is a small chemotactic protein and a key player in initiating the early immune
response. As an adipokine, chemerin is also involved in energy homeostasis and the …
response. As an adipokine, chemerin is also involved in energy homeostasis and the …
Structural basis of ligand binding modes at the neuropeptide YY1 receptor
Z Yang, S Han, M Keller, A Kaiser, BJ Bender, M Bosse… - Nature, 2018 - nature.com
Neuropeptide Y (NPY) receptors belong to the G-protein-coupled receptor superfamily and
have important roles in food intake, anxiety and cancer biology,. The NPY–Y receptor …
have important roles in food intake, anxiety and cancer biology,. The NPY–Y receptor …
[HTML][HTML] Structural basis for ligand recognition of the neuropeptide YY2 receptor
T Tang, C Hartig, Q Chen, W Zhao, A Kaiser… - Nature …, 2021 - nature.com
The human neuropeptide Y (NPY) Y2 receptor (Y2R) plays essential roles in food intake,
bone formation and mood regulation, and has been considered an important drug target for …
bone formation and mood regulation, and has been considered an important drug target for …
The design of a GLP‐1/PYY dual acting agonist
S Østergaard, JF Paulsson… - Angewandte Chemie …, 2021 - Wiley Online Library
The two gut hormones GLP‐1 and PYY3–36, which are both secreted from the L‐cells upon
food stimuli, have a stronger inhibitory effect on food intake when they are combined …
food stimuli, have a stronger inhibitory effect on food intake when they are combined …
Cyclic analogues of the chemerin C-terminus mimic a loop conformation essential for activating the chemokine-like receptor 1
TF Fischer, CT Schoeder, T Zellmann… - Journal of Medicinal …, 2021 - ACS Publications
The chemokine-like receptor 1 (CMKLR1) is a promising target for treating autoinflammatory
diseases, cancer, and reproductive disorders. However, the interaction between CMKLR1 …
diseases, cancer, and reproductive disorders. However, the interaction between CMKLR1 …
[HTML][HTML] Small-molecule ligands as challenge for positron emission tomography of peptide receptors in neurons and microglia of the brain
M Pissarek - World Journal of Neuroscience, 2019 - scirp.org
Neuropeptide and chemokine receptors of the G protein-coupled receptor (GPCR) family
belong to different classes and subgroups providing different docking sites and special …
belong to different classes and subgroups providing different docking sites and special …
Knowledge-Based Modeling of G-Protein Coupled Receptors and their Binding Partners
BJ Bender - 2019 - ir.vanderbilt.edu
G-protein coupled receptors (GPCRs) represent the largest family of membrane proteins and
the most heavily targeted classes of proteins for therapeutic intervention. Relatively little is …
the most heavily targeted classes of proteins for therapeutic intervention. Relatively little is …