Large-scale comparative assessment of computational predictors for lysine post-translational modification sites

Z Chen, X Liu, F Li, C Li, T Marquez-Lago… - Briefings in …, 2019 - academic.oup.com
Lysine post-translational modifications (PTMs) play a crucial role in regulating diverse
functions and biological processes of proteins. However, because of the large volumes of …

iLearn: an integrated platform and meta-learner for feature engineering, machine-learning analysis and modeling of DNA, RNA and protein sequence data

Z Chen, P Zhao, F Li, TT Marquez-Lago… - Briefings in …, 2020 - academic.oup.com
With the explosive growth of biological sequences generated in the post-genomic era, one
of the most challenging problems in bioinformatics and computational biology is to …

In silico approaches for the prediction and analysis of antiviral peptides: a review

P Charoenkwan, N Anuwongcharoen… - Current …, 2021 - ingentaconnect.com
In light of the growing resistance toward current antiviral drugs, efforts to discover novel and
effective antiviral therapeutic agents remain a pressing scientific effort. Antiviral peptides …

Improving protein succinylation sites prediction using embeddings from protein language model

S Pokharel, P Pratyush, M Heinzinger, RH Newman… - Scientific reports, 2022 - nature.com
Protein succinylation is an important post-translational modification (PTM) responsible for
many vital metabolic activities in cells, including cellular respiration, regulation, and repair …

PreAIP: computational prediction of anti-inflammatory peptides by integrating multiple complementary features

MS Khatun, MM Hasan, H Kurata - Frontiers in genetics, 2019 - frontiersin.org
Numerous inflammatory diseases and autoimmune disorders by therapeutic peptides have
received substantial consideration; however, the exploration of anti-inflammatory peptides …

DeepSuccinylSite: a deep learning based approach for protein succinylation site prediction

N Thapa, M Chaudhari, S McManus, K Roy… - BMC …, 2020 - Springer
Background Protein succinylation has recently emerged as an important and common post-
translation modification (PTM) that occurs on lysine residues. Succinylation is notable both …

Inspector: a lysine succinylation predictor based on edited nearest-neighbor undersampling and adaptive synthetic oversampling

Y Zhu, C Jia, F Li, J Song - Analytical biochemistry, 2020 - Elsevier
Lysine succinylation is an important type of protein post-translational modification and plays
a key role in regulating protein function and structural changes. The mechanism and …

Prediction of S-nitrosylation sites by integrating support vector machines and random forest

MM Hasan, B Manavalan, MS Khatun, H Kurata - Molecular omics, 2019 - pubs.rsc.org
Cysteine S-nitrosylation is a type of reversible post-translational modification of proteins,
which controls diverse biological processes. It is associated with redox-based cellular …

dForml (KNN)-PseAAC: Detecting formylation sites from protein sequences using K-nearest neighbor algorithm via Chou's 5-step rule and pseudo components

Q Ning, Z Ma, X Zhao - Journal of theoretical biology, 2019 - Elsevier
Formylation is a type of post-translational modification that can occur on lysine sites, which
plays an irreplaceable role in organism. To better understand the mechanism, it is necessary …

GPSuc: Global Prediction of Generic and Species-specific Succinylation Sites by aggregating multiple sequence features

MM Hasan, H Kurata - PloS one, 2018 - journals.plos.org
Lysine succinylation is one of the dominant post-translational modification of the protein that
contributes to many biological processes including cell cycle, growth and signal transduction …