We review the current knowledge on the use of single-molecule force spectroscopy
techniques to extrapolate the elastic properties of nucleic acids. We emphasize the lesser …

In this review we focus on the idea of establishing connections between the mechanical
properties of DNA–ligand complexes and the physical chemistry of DNA–ligand interactions …

Single-stranded DNA (ssDNA) plays a major role in several biological processes. It is
therefore of fundamental interest to understand how the elastic response and the formation …

Faithful segregation of bacterial chromosomes relies on the ParABS partitioning system and
the SMC complex. In this work, we used single-molecule techniques to investigate the role of …

Temperature is a well-defined quantity for systems in equilibrium. For glassy systems, it has
been extended to the non-equilibrium regime, showing up as an effective quantity in a …

We have investigated the interaction of the DNA molecule with the anticancer drug
doxorubicin (doxo) by using three different experimental techniques: single molecule …

The folding of biological macromolecules is a fundamental process of which we lack a full
comprehension. Mostly studied in proteins and RNA, single-stranded DNA (ssDNA) also …

The interactions between biomolecules and material interfaces at the molecular level are
complicated but very important for the development of materials science, nanotechnology …

Most DNA processes are governed by molecular interactions that take place in a sequence-
specific manner. Determining the sequence selectivity of DNA ligands is still a challenge …

Abstract A-tracts are A: T rich DNA sequences that exhibit unique structural and mechanical
properties associated with several functions in vivo. The crystallographic structure of A-tracts …