Catecholaminergic systems in stress: structural and molecular genetic approaches

R Kvetnansky, EL Sabban… - Physiological …, 2009 - journals.physiology.org
Stressful stimuli evoke complex endocrine, autonomic, and behavioral responses that are
extremely variable and specific depending on the type and nature of the stressors. We first …

Potential role of insulin on the pathogenesis of depression

XH Zou, LH Sun, W Yang, BJ Li, RJ Cui - Cell proliferation, 2020 - Wiley Online Library
The regulation of insulin on depression and depression‐like behaviour has been widely
reported. Insulin and activation of its receptor can promote learning and memory, affect the …

Recurrent hypoglycemia inhibits the counterregulatory response by suppressing adrenal activity

Y Ma, Q Wang, D Joe, M Wang… - The Journal of clinical …, 2018 - Am Soc Clin Investig
Hypoglycemia activates the counterregulatory response (CRR), a neural-endocrine reflex
that restores euglycemia. Although effective if occasionally activated, repeated induction of …

Rethinking the genetic basis for comorbidity of schizophrenia and type 2 diabetes

PI Lin, AR Shuldiner - Schizophrenia research, 2010 - Elsevier
The co-occurrence of schizophrenia (SCZ) and type 2 diabetes mellitus (T2D) has been well
documented. This review article focuses on the hypothesis that the co-occurrence of SCZ …

Catecholamines-based myocardial injury after acute ischemic stroke and effects of Naoxintong capsule therapy

Y Ouyang, S Hu, M Chang, J Xu, G Tian, X Kong, J Liu… - Phytomedicine, 2024 - Elsevier
Background Myocardial injury (MI) after acute ischemic stroke (AIS) poses a significant
threat to patient prognosis. However, effective intervention strategies are currently lacking …

Stress-induced catecholaminergic function: transcriptional and post-transcriptional control

DL Wong, AW Tank - Stress, 2007 - Taylor & Francis
This review summarizes knowledge on the effects of stress on two catecholamine
biosynthetic enzymes, tyrosine hydroxylase (TH) and phenylethanolamine N …

Impaired basal and restraint-induced epinephrine secretion in corticotropin-releasing hormone-deficient mice

KH Jeong, L Jacobson, K Pacák, EP Widmaier… - …, 2000 - academic.oup.com
CRH is thought to play a role in responses of the adrenocortical and adrenomedullary
systems during stress. To investigate the role of CRH in stress-induced secretions of …

Effect of novel stressors on gene expression of tyrosine hydroxylase and monoamine transporters in brainstem noradrenergic neurons of long-term repeatedly …

M Rusnák, R Kvetňanský, J Jeloková, M Palkovits - Brain research, 2001 - Elsevier
Responses of central noradrenergic (NE) neurons to stressors like immobilization (IMO),
cold exposure, insulin-induced hypoglycemia, and cellular glucoprivation caused by 2 …

Neuropeptide y gates a stress-induced, long-lasting plasticity in the sympathetic nervous system

Q Wang, M Wang, MD Whim - Journal of Neuroscience, 2013 - Soc Neuroscience
Acute stress evokes the fight-or-flight reflex, which via release of the catecholamine
hormones affects the function of every major organ. Although the reflex is transient, it has …

Role of the Adrenal Medulla in Hypoglycaemia-Associated Autonomic Failure—A Diabetic Perspective

M Senthilkumaran, C Koch, MF Herselman… - Metabolites, 2024 - mdpi.com
Hypoglycaemia-associated autonomic failure (HAAF) is characterised by an impairment in
adrenal medullary and neurogenic symptom responses following episodes of recurrent …