Fibroblast growth factor 21 and the adaptive response to nutritional challenges

Ú Martínez-Garza, D Torres-Oteros… - International journal of …, 2019 - mdpi.com
The Fibroblast Growth Factor 21 (FGF21) is considered an attractive therapeutic target for
obesity and obesity-related disorders due to its beneficial effects in lipid and carbohydrate …

Adapting to the cold: a role for endogenous fibroblast growth factor 21 in thermoregulation?

M Klein Hazebroek, S Keipert - Frontiers in Endocrinology, 2020 - frontiersin.org
Fibroblast growth factor 21 (FGF21) is in biomedical focus as a treatment option for
metabolic diseases, given that administration improves metabolism in mice and humans …

Short‐term protein restriction at advanced age stimulates FGF21 signalling, energy expenditure and browning of white adipose tissue

MB Dommerholt, M Blankestijn… - The FEBS …, 2021 - Wiley Online Library
Dietary protein restriction has been demonstrated to improve metabolic health under various
conditions. However, the relevance of ageing and age‐related decline in metabolic flexibility …

Black bean protein concentrate ameliorates hepatic steatosis by decreasing lipogenesis and increasing fatty acid oxidation in rats fed a high fat-sucrose diet

I Hernandez-Velazquez, M Sanchez-Tapia… - Food & function, 2020 - pubs.rsc.org
The black bean is a legume widely consumed in Latin America, however its consumption
has decreased significantly in recent decades. There is evidence that its consumption …

[HTML][HTML] Role of glucocorticoid receptor (GR) in white adipose tissue beiging

FM Martín, A Alzamendi, AE Harnichar… - Life Sciences, 2023 - Elsevier
Abstract Aim Glucocorticoids (GCs) play a crucial role in energy homeostasis including white
adipose tissue function; however, chronic GC excess is detrimental to mammals' health …

Alternatively spliced MBNL1 isoforms exhibit differential influence on enhancing brown adipogenesis

CS Hung, JC Lin - Biochimica et Biophysica Acta (BBA)-Gene Regulatory …, 2020 - Elsevier
Browning of white adipocytes (WAs)(also referred as beige cells) was demonstrated to
execute thermogenesis by consuming stored lipids as do brown adipocytes (BAs), and this …

Maternal high fructose diet exacerbates white adipose tissue thermogenic process in offspring upon exposure to cold temperature

A Alzamendi, I Miguel, MG Zubiría, SE Gambaro… - Life Sciences, 2021 - Elsevier
Aim An adverse endogenous environment during early life predisposes to metabolic
disorder development. We previously reported adverse metabolic and adipose tissue effects …

Activation of brown adipose tissue by a low-protein diet ameliorates hyperglycemia in a diabetic lipodystrophy mouse model

MD Munoz, A Zamudio, M McCann, V Gil, P Xu… - Scientific Reports, 2023 - nature.com
Long-term ad libitum dietary restrictions, such as low-protein diets (LPDs), improve
metabolic health and extend the life span of mice and humans. However, most studies …

Efecto de la ovariectomía prepuberal sobre la función del tejido adiposo blanco abdominal y subcutáneo

I Miguel - 2023 - sedici.unlp.edu.ar
Nuestra hipótesis a ser puesta a prueba se basa en que “la castración prepuberal en la rata
hembra provoca el desarrollo anormal del tejido adiposo blanco, lo cual genera un impacto …

Undernutrition induces major alterations in the lipid droplets of white and brown adipose tissues in wistar rats

C Rodríguez-Rivera, LS Moreda, LF Alguacil, F Escrivá… - Tissue and Cell, 2021 - Elsevier
Several studies have shown a relationship between the distribution of fat mass around the
organism, metabolic disorders, and an increased risk of morbidity and mortality. It has been …