Glioblastoma multiforme (GBM): An overview of current therapies and mechanisms of resistance

W Wu, JL Klockow, M Zhang, F Lafortune… - Pharmacological …, 2021 - Elsevier
Glioblastoma multiforme (GBM) is a WHO grade IV glioma and the most common malignant,
primary brain tumor with a 5-year survival of 7.2%. Its highly infiltrative nature, genetic …

Exosomes and cancer-Diagnostic and prognostic biomarkers and therapeutic vehicle

X Wang, L Tian, J Lu, IOL Ng - Oncogenesis, 2022 - nature.com
Exosomes belong to a subpopulation of extracellular vesicles secreted by the dynamic
multistep endocytosis process and carry diverse functional molecular cargoes, including …

Understanding the extracellular vesicle surface for clinical molecular biology

S Hallal, Á Tűzesi, GE Grau… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) are lipid‐membrane enclosed nanoparticles that play significant
roles in health and disease. EVs are abundant in body fluids and carry an array of molecules …

GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis

YJ Lee, KJ Shin, HJ Jang, JS Ryu, CY Lee, JH Yoon… - Developmental cell, 2023 - cell.com
Exosomes transport a variety of macromolecules and modulate intercellular communication
in physiology and disease. However, the regulation mechanisms that determine exosome …

Circulating biomarkers in patients with glioblastoma

J Müller Bark, A Kulasinghe, B Chua, BW Day… - British journal of …, 2020 - nature.com
Gliomas are the most common tumours of the central nervous system and the most
aggressive form is glioblastoma (GBM). Despite advances in treatment, patient survival …

Current and future trends on diagnosis and prognosis of glioblastoma: from molecular biology to proteomics

AS Silantyev, L Falzone, M Libra, OI Gurina… - Cells, 2019 - mdpi.com
Glioblastoma multiforme is the most aggressive malignant tumor of the central nervous
system. Due to the absence of effective pharmacological and surgical treatments, the …

[HTML][HTML] Extracellular vesicles: the next generation of biomarkers for liquid biopsy-based prostate cancer diagnosis

B Pang, Y Zhu, J Ni, J Thompson, D Malouf, J Bucci… - Theranostics, 2020 - ncbi.nlm.nih.gov
Prostate cancer (PCa) is a leading cause of cancer death for males in western countries.
The current gold standard for PCa diagnosis-template needle biopsies-often does not …

[HTML][HTML] Small extracellular vesicles in cancer

K Abhange, A Makler, Y Wen, N Ramnauth, W Mao… - Bioactive Materials, 2021 - Elsevier
Extracellular vesicles (EV) are lipid-bilayer enclosed vesicles in submicron size that are
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …

Extracellular vesicles in liquid biopsies as biomarkers for solid tumors

B Irmer, S Chandrabalan, L Maas, A Bleckmann… - Cancers, 2023 - mdpi.com
Simple Summary During the past decade, liquid biopsy-related publications have increased
exponentially, demonstrating the great potential of screening body fluids for diagnosis …

microRNAs (miRNAs) in glioblastoma multiforme (GBM)—recent literature review

M Makowska, B Smolarz, H Romanowicz - International Journal of …, 2023 - mdpi.com
Glioblastoma multiforme (GBM) is the most common, malignant, poorly promising primary
brain tumor. GBM is characterized by an infiltrating growth nature, abundant vascularization …