Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces
severe neural injuries, and is one of the leading causes of death and disability worldwide …

Cerebral ischemic stroke is characterized by acute ischemia in a certain part of the brain,
which leads to brain cells necrosis, apoptosis, ferroptosis, pyroptosis, etc. At present, there …

The cerebral ischemia injury can result in neuronal death and/or functional impairment,
which leads to further damage and dysfunction after recovery of blood supply. Cerebral …

Ligusticum chuanxiong Hort (known as Chuanxiong in China, CX) is one of the most widely
used and long-standing medicinal herbs in China. Tetramethylpyrazine (TMP) is an alkaloid …

Stroke is a leading cause of death and disability worldwide, and approximately 87% of
cases are attributed to ischemia. The main factors that cause ischemic stroke include …

Stroke is one of the leading causes of death and disability in the world. Oxidative stress,
which refers to an excessive generation of reactive oxygen species (ROS), plays a key role …

Ischemic stroke, characterized by the sudden loss of blood flow in specific area (s) of the
brain, is the leading cause of permanent disability and is among the leading causes of death …

Ischemic stroke is one of the leading causes of death and long-term disability worldwide;
however, effective clinical approaches are still limited. The transcriptional factor Nrf2 is a …

The present study aimed to investigate the anti‑ferroptosis effects of the HMGB1 inhibitor
glycyrrhizin (GLY). The present study used a cell and animal model of acute liver failure …

One of the major causes of long-term disability and mortality is ischemic stroke that enjoys
limited treatment approaches. On the one hand, oxidative stress, induced by excessive …