[HTML][HTML] On a highway to the brain: A review on nose-to-brain drug delivery using nanoparticles

ML Formica, DA Real, ML Picchio, E Catlin… - Applied Materials …, 2022 - Elsevier
The administration of drugs to the central nervous system (CNS) is primarily controlled by
the blood-brain barrier (BBB), a structure that prevents the passage of foreign compounds …

Beyond PM2. 5: The role of ultrafine particles on adverse health effects of air pollution

R Chen, B Hu, Y Liu, J Xu, G Yang, D Xu… - Biochimica et Biophysica …, 2016 - Elsevier
Background Air pollution constitutes the major threat to human health, whereas their
adverse impacts and underlying mechanisms of different particular matters are not clearly …

Airborne particulate matter: human exposure and health effects

JE Thompson - Journal of occupational and environmental …, 2018 - journals.lww.com
Objective: Exposure to airborne particulate matter (PM) is estimated to cause millions of
premature deaths annually. This work conveys known routes of exposure to PM and …

Nanoparticle technology and stem cell therapy team up against neurodegenerative disorders

C Vissers, G Ming, H Song - Advanced drug delivery reviews, 2019 - Elsevier
The convergence of nanoparticles and stem cell therapy holds great promise for the study,
diagnosis, and treatment of neurodegenerative disorders. Researchers aim to harness the …

[HTML][HTML] In-utero exposure to air pollution and early-life neural development and cognition

C Yi, Q Wang, Y Qu, J Niu, BG Oliver, H Chen - … and environmental safety, 2022 - Elsevier
Air pollution remains one of the major health threats around the world. Compared to adults,
foetuses and infants are more vulnerable to the effects of environmental toxins. Maternal …

Olfactory deposition of inhaled nanoparticles in humans

GJM Garcia, JD Schroeter, JS Kimbell - Inhalation toxicology, 2015 - Taylor & Francis
Context: Inhaled nanoparticles can migrate to the brain via the olfactory bulb, as
demonstrated in experiments in several animal species. This route of exposure may be the …

Application of quantum dots in brain diseases and their neurotoxic mechanism

Y Hu, X Wang, Y Niu, K He, M Tang - Nanoscale Advances, 2024 - pubs.rsc.org
The early-stage diagnosis and therapy of brain diseases pose a persistent challenge in the
field of biomedicine. Quantum dots (QDs), nano-luminescent materials known for their small …

Nasal-nanotechnology: revolution for efficient therapeutics delivery

A Kumar, AN Pandey, SK Jain - Drug delivery, 2016 - Taylor & Francis
Context: In recent years, nanotechnology-based delivery systems have gained interest to
overcome the problems of restricted absorption of therapeutic agents from the nasal cavity …

Toxicity of metallic nanoparticles in the central nervous system

K Sawicki, M Czajka, M Matysiak-Kucharek… - Nanotechnology …, 2019 - degruyter.com
Metallic nanoparticles due to their small size and unique physico-chemical characteristics
have found excellent applications in various branches of industry and medicine. Therefore …

Biochemistry and biomedicine of quantum dots: from biodetection to bioimaging, drug discovery, diagnostics, and therapy

J Yao, P Li, L Li, M Yang - Acta biomaterialia, 2018 - Elsevier
According to recent research, nanotechnology based on quantum dots (QDs) has been
widely applied in the field of bioimaging, drug delivery, and drug analysis. Therefore, it has …