Polymeric micelles for the delivery of poorly soluble drugs: From nanoformulation to clinical approval

D Hwang, JD Ramsey, AV Kabanov - Advanced drug delivery reviews, 2020 - Elsevier
Over the last three decades, polymeric micelles have emerged as a highly promising drug
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …

[HTML][HTML] Polymersome-based protein drug delivery–quo vadis?

MG Gouveia, JP Wesseler, J Ramaekers… - Chemical Society …, 2023 - pubs.rsc.org
Protein-based therapeutics are an attractive alternative to established therapeutic
approaches and represent one of the fastest growing families of drugs. While many of these …

Form follows function: nanoparticle shape and its implications for nanomedicine

C Kinnear, TL Moore, L Rodriguez-Lorenzo… - Chemical …, 2017 - ACS Publications
This review is a comprehensive description of the past decade of research into
understanding how the geometry and size of nanoparticles affect their interaction with …

Liposomes as nanomedical devices

G Bozzuto, A Molinari - International journal of nanomedicine, 2015 - Taylor & Francis
Since their discovery in the 1960s, liposomes have been studied in depth, and they continue
to constitute a field of intense research. Liposomes are valued for their biological and …

Mechanisms and biomaterials in pH-responsive tumour targeted drug delivery: a review

M Kanamala, WR Wilson, M Yang, BD Palmer, Z Wu - Biomaterials, 2016 - Elsevier
As the mainstay in the treatment of various cancers, chemotherapy plays a vital role, but still
faces many challenges, such as poor tumour selectivity and multidrug resistance (MDR) …

Self-assembly of block copolymers

Y Mai, A Eisenberg - Chemical Society Reviews, 2012 - pubs.rsc.org
Block copolymer (BCP) self-assembly has attracted considerable attention for many
decades because it can yield ordered structures in a wide range of morphologies, including …

[HTML][HTML] Approved nanomedicine against diseases

Y Jia, Y Jiang, Y He, W Zhang, J Zou, KT Magar… - Pharmaceutics, 2023 - mdpi.com
Nanomedicine is a branch of medicine using nanotechnology to prevent and treat diseases.
Nanotechnology represents one of the most effective approaches in elevating a drug's …

Minimal" Self" peptides that inhibit phagocytic clearance and enhance delivery of nanoparticles

PL Rodriguez, T Harada, DA Christian, DA Pantano… - Science, 2013 - science.org
Foreign particles and cells are cleared from the body by phagocytes that must also
recognize and avoid clearance of" self" cells. The membrane protein CD47 is reportedly a" …

Endocytosis at the nanoscale

I Canton, G Battaglia - Chemical Society Reviews, 2012 - pubs.rsc.org
Endocytosis is a fundamental process in which eukaryotic cells internalise molecules and
macromolecules via deformation of the membrane and generation of membrane-bound …

Polymer-based nanocapsules for drug delivery

CE Mora-Huertas, H Fessi, A Elaissari - International journal of …, 2010 - Elsevier
A review of the state of knowledge on nanocapsules prepared from preformed polymers as
active substances carriers is presented. This entails a general review of the different …