Abstract Background Next Generation Sequencing (NGS) experiments produce millions of
short sequences that, mapped to a reference genome, provide biological insights at …

Introduction and hypothesis The objective was to systemically review the current literature
on the association of gut, vaginal, and urinary dysbiosis in female patients with overactive …

Gene regulatory grids (GRGs) encompass the space of all the possible transcription factor
(TF)–target gene interactions that regulate gene expression, with gene regulatory networks …

In order to survive, all organism require sugars, amino acids and lipids, which are used for
energy and growth. The nutritional needs of an organism vary tremendously between …

Developing a knowledge base that contains all the information necessary for the researcher
studying gene regulation in a particular organism can be accomplished in four stages. This …

Reads alignment is an essential step of next generation sequencing) data analyses. One
challenging issue is represented by unmapped reads that are usually discarded and …

Furthermore, I want to thank all Postdocs in the Schultze group for their constant attendance
to give competent support no matter if it was day or night, especially Dr. Susanne V. Schmidt …

Approximately 8.5 million people in the UK are affected by osteoarthritis (OA), a
multifactorial, polygenic disease characterised by articular cartilage loss. In 2012, the …