The substitution of primary or secondary alcohols with nucleophiles mediated by a redox
combination of a trialkylor triarylphosphine and a dialkyl azodicarboxylate is popularly …

In the development of new systems for asymmetric synthesis it has always been a big
challenge to obtain optically active compounds with good yields and selectivities. For this …

Desymmetrization of meso compounds to yield chiral products proved to be a powerful
synthetic tool in asymmetric synthesis since it allows formation of multiple stereogenic …

Recent years have witnessed increasing interest in the field of asymmetric organocatalysis.
In particular, efforts in this field have been devoted to the use of small organic molecules in …

A unique example of the one‐pot trans‐diastereoselective reaction of meso‐tricyclic
anhydrides is reported. The process involves anhydride ring opening by an amidoxime and …

A novel two-step synthesis of β-trifluoromethyl primary amines from readily available α-
(trifluoromethyl) styrenes and phthalimide is developed. The first step involves a …

Readily available, low molecular cyclohexane-based organocatalysts promote highly
enantioselective desymmetrizations of cyclic meso-anhydrides applying alcohols and benzyl …

Both ureas and thioureas derived from l-or d-valine act as bifunctional organocatalysts able
to induce the enantioselective alcoholysis of mono-, bi-, and tricyclic meso anhydrides. The …

Asymmetric thiolysis of prochiral cyclic anhydrides was achieved with our developed chiral
sulfonamide and squaramide bifunctional organocatalysts based on amino alcohol …

The asymmetric synthesis of cis-1, 4-amino alcohols with a norbornene backbone was
performed starting with (2S, 3R)-(−)-cis-hemiester 2 (98% ee). Chemoselective amination …