Towards enzymatic breakdown of complex plant xylan structures: state of the art

P Biely, S Singh, V Puchart - Biotechnology Advances, 2016 - Elsevier
Significant progress over the past few years has been achieved in the enzymology of
microbial degradation and saccharification of plant xylan, after cellulose being the most …

Biochemistry of complex glycan depolymerisation by the human gut microbiota

D Ndeh, HJ Gilbert - FEMS microbiology reviews, 2018 - academic.oup.com
The human gut microbiota (HGM) makes an important contribution to health and disease. It
is a complex microbial community of trillions of microbes with a majority of its members …

Complex pectin metabolism by gut bacteria reveals novel catalytic functions

D Ndeh, A Rogowski, A Cartmell, AS Luis, A Baslé… - Nature, 2017 - nature.com
The metabolism of carbohydrate polymers drives microbial diversity in the human gut
microbiota. It is unclear, however, whether bacterial consortia or single organisms are …

Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides

AS Luis, J Briggs, X Zhang, B Farnell, D Ndeh… - Nature …, 2018 - nature.com
The major nutrients available to human colonic Bacteroides species are glycans,
exemplified by pectins, a network of covalently linked plant cell wall polysaccharides …

Recognition and degradation of plant cell wall polysaccharides by two human gut symbionts

EC Martens, EC Lowe, H Chiang, NA Pudlo, M Wu… - PLoS …, 2011 - journals.plos.org
Symbiotic bacteria inhabiting the human gut have evolved under intense pressure to utilize
complex carbohydrates, primarily plant cell wall glycans in our diets. These polysaccharides …

A discrete genetic locus confers xyloglucan metabolism in select human gut Bacteroidetes

J Larsbrink, TE Rogers, GR Hemsworth, LS McKee… - Nature, 2014 - nature.com
A well-balanced human diet includes a significant intake of non-starch polysaccharides,
collectively termed 'dietary fibre', from the cell walls of diverse fruits and vegetables. Owing …

Production, characteristics, and biotechnological applications of microbial xylanases

Alokika, B Singh - Applied microbiology and biotechnology, 2019 - Springer
Microbial xylanases have gathered great attention due to their biotechnological potential at
industrial scale for many processes. A variety of lignocellulosic materials, such as sugarcane …

A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation

A Cartmell, J Muñoz-Muñoz, JA Briggs, DA Ndeh… - Nature …, 2018 - nature.com
Glycans are major nutrients for the human gut microbiota (HGM). Arabinogalactan proteins
(AGPs) comprise a heterogenous group of plant glycans in which a β1, 3-galactan backbone …

Plant glycan metabolism by bifidobacteria

SM Kelly, J Munoz-Munoz… - Frontiers in Microbiology, 2021 - frontiersin.org
Members of the genus Bifidobacterium, of which the majority have been isolated as gut
commensals, are Gram-positive, non-motile, saccharolytic, non-sporulating, anaerobic …

Communal living: glycan utilization by the human gut microbiota

JA Briggs, JM Grondin, H Brumer - Environmental Microbiology, 2021 - Wiley Online Library
Our lower gastrointestinal tract plays host to a vast consortium of microbes, known as the
human gut microbiota (HGM). The HGM thrives on a complex and diverse range of glycan …