Integration of innate immune signaling

CA Thaiss, M Levy, S Itav, E Elinav - Trends in immunology, 2016 - cell.com
The last decades of research in innate immunology have revealed a multitude of sensing
receptors that evaluate the presence of microorganisms or cellular damage in tissues. In the …

Nucleic acids and endosomal pattern recognition: how to tell friend from foe?

E Brencicova, SS Diebold - Frontiers in cellular and infection …, 2013 - frontiersin.org
The innate immune system has evolved endosomal and cytoplasmic receptors for the
detection of viral nucleic acids as sensors for virus infection. Some of these pattern …

Lactobacillus acidophilus induces virus immune defence genes in murine dendritic cells by a Toll‐like receptor‐2‐dependent mechanism

G Weiss, S Rasmussen, LH Zeuthen, BN Nielsen… - …, 2010 - Wiley Online Library
Lactobacilli are probiotics that, among other health‐promoting effects, have been ascribed
immunostimulating and virus‐preventive properties. Certain Lactobacillus spp. have been …

Human Toll-like receptor 8 (TLR8) is an important sensor of pyogenic bacteria, and is attenuated by cell surface TLR signaling

SH Moen, B Ehrnström, JF Kojen… - Frontiers in …, 2019 - frontiersin.org
TLR8 is an endosomal sensor of RNA degradation products in human phagocytes, and is
involved in the recognition of viral and bacterial pathogens. We previously showed that in …

Pseudomonas aeruginosa LasB Subverts Alveolar Macrophage Activity by Interfering With Bacterial Killing Through Downregulation of Innate Immune Defense …

F Bastaert, S Kheir, V Saint-Criq, B Villeret… - Frontiers in …, 2018 - frontiersin.org
Pseudomonas aeruginosa (Pa) is a pathogen causing significant morbidity and mortality, in
particular, in hospital patients undergoing ventilation and in patients with cystic fibrosis …

Pseudomonas aeruginosa Type-3 Secretion System Dampens Host Defense by Exploiting the NLRC4-coupled Inflammasome

E Faure, JB Mear, K Faure, S Normand… - American journal of …, 2014 - atsjournals.org
Rationale: Pseudomonas aeruginosa, a major problem pathogen responsible for severe
infections in critically ill patients, triggers, through a functional type-3 secretion system …

Carbohydrates from Pseudomonas aeruginosa biofilms interact with immune C-type lectins and interfere with their receptor function

S Singh, Y Almuhanna, MY Alshahrani… - npj Biofilms and …, 2021 - nature.com
Bacterial biofilms represent a challenge to the healthcare system because of their resilience
against antimicrobials and immune attack. Biofilms consist of bacterial aggregates …

Toll-like receptors in the host defense against Pseudomonas aeruginosa respiratory infection and cystic fibrosis

SM McIsaac, AW Stadnyk, TJ Lin - Journal of leukocyte biology, 2012 - academic.oup.com
Review of innate cell TLR activation by Pseudomonas aeruginosa to explain lung
inflammation during cystic fibrosis, and the prospects of preventing infection. TLRs function …

[图书][B] Animal lectins: form, function and clinical applications

GS Gupta - 2012 - books.google.com
Animal Lectins: Form, Function and Clinical Applications presents up-to-date knowledge of
animal lectins. Detailed descriptions on biological activities, tissue and/or subcellular …

[HTML][HTML] Hemocyanins stimulate innate immunity by inducing different temporal patterns of proinflammatory cytokine expression in macrophages

TY Zhong, S Arancibia, R Born, R Tampe… - The Journal of …, 2016 - journals.aai.org
Hemocyanins induce a potent Th1-dominant immune response with beneficial clinical
outcomes when used as a carrier/adjuvant in vaccines and nonspecific immunostimulant in …