Structural and immunological principles leading to chemically synthesized, multiantigenic, multistage, minimal subunit-based vaccine development
Dedicated to the memory of Professors Henry G. Kunkel and Bruce Merrifield (Rockefeller
University, New York), who introduced us to the fascinating worlds of immunology and …
University, New York), who introduced us to the fascinating worlds of immunology and …
What Is Known about the Immune Response Induced by Plasmodium vivax Malaria Vaccine Candidates?
C López, Y Yepes-Pérez, N Hincapié-Escobar… - Frontiers in …, 2017 - frontiersin.org
Malaria caused by Plasmodium vivax continues being one of the most important infectious
diseases around the world; P. vivax is the second most prevalent species and has the …
diseases around the world; P. vivax is the second most prevalent species and has the …
Specific Interaction between Mycobacterium tuberculosis Lipoprotein‐derived Peptides and Target Cells Inhibits Mycobacterial Entry In Vitro
Tuberculosis (TB) continues being one of the diseases having the greatest mortality rates
around the world, 8.7 million cases having been reported in 2011. An efficient vaccine …
around the world, 8.7 million cases having been reported in 2011. An efficient vaccine …
IMPIPS: The Im mune P rotection-I nducing P rotein S tructure Concept in the Search for Steric-Electron and Topochemical Principles for Complete Fully-Protective …
Determining immune protection-inducing protein structures (IMPIPS) involves defining the
stereo-electron and topochemical characteristics which are essential in MHC-p-TCR …
stereo-electron and topochemical characteristics which are essential in MHC-p-TCR …
Mce4F Mycobacterium tuberculosis protein peptides can inhibit invasion of human cell lines
DC Rodríguez, M Ocampo, Y Varela… - Pathogens and …, 2015 - academic.oup.com
This work was aimed at studying the Mycobacterium tuberculosis H37Rv Rv3494c protein,
taking into account that it belongs to the mammalian cell entry family (mce) which is thought …
taking into account that it belongs to the mammalian cell entry family (mce) which is thought …
[HTML][HTML] Immune protection-inducing protein structures (IMPIPS) against malaria: the weapons needed for beating Odysseus
The review covers the functional and structural approach followed by our group for more
than 34 years in the search for a methodology that allows the rational design of chemically …
than 34 years in the search for a methodology that allows the rational design of chemically …
Recent advances in the development of a chemically synthesised anti-malarial vaccine
H Curtidor, ME Patarroyo… - Expert Opinion on …, 2015 - Taylor & Francis
Introduction: Obtaining an effective antimalarial vaccine has represented one of the biggest
public health challenges over the last 50 years. Despite efforts by many laboratories around …
public health challenges over the last 50 years. Despite efforts by many laboratories around …
Functional, immunological and three-dimensional analysis of chemically synthesised sporozoite peptides as components of a fully-effective antimalarial vaccine
H Curtidor, M Vanegas, MP Alba… - Current medicinal …, 2011 - ingentaconnect.com
Our ongoing search for a fully-effective vaccine against the Plasmodium falciparum parasite
(causing the most lethal form of human malaria) has been focused on identifying and …
(causing the most lethal form of human malaria) has been focused on identifying and …
Conserved binding regions provide the clue for peptide-based vaccine development: a chemical perspective
Synthetic peptides have become invaluable biomedical research and medicinal chemistry
tools for studying functional roles, ie, binding or proteolytic activity, naturally-occurring …
tools for studying functional roles, ie, binding or proteolytic activity, naturally-occurring …
Biological and structural characteristics of the binding peptides from the sporozoite proteins essential for cell traversal (SPECT)-1 and-2
ME Patarroyo, MP Alba, H Curtidor - Peptides, 2011 - Elsevier
The sporozoite microneme proteins essential for cell traversal, SPECT-1 and SPECT-2, are
considered attractive pre-erythrocytic immune targets due to the key role they play in …
considered attractive pre-erythrocytic immune targets due to the key role they play in …