Modern Synthetic Strategies with Organoselenium Reagents: A Focus on Vinyl Selenones

M Palomba, I Franco Coelho Dias, O Rosati, F Marini - Molecules, 2021 - mdpi.com
In recent years, vinyl selenones were rediscovered as useful building blocks for new
synthetic transformations. This review will highlight these advances in the field of multiple …

Synthesis of Oxazino [4, 3-a] indoles and biological applications

S Pecnard, A Hamze, JL Pozzo, M Alami… - European Journal of …, 2021 - Elsevier
This review brings together the various pathways to the oxazino [4, 3-a] indole motif over the
last decades. Representative examples showing the scope of these processes will illustrate …

Iodine/Oxone® oxidative system for the synthesis of selenylindoles bearing a benzenesulfonamide moiety as carbonic anhydrase I, II, IX, and XII inhibitors

M Palomba, A Angeli, R Galdini… - Organic & …, 2024 - pubs.rsc.org
A wide range of 3-selenylindoles were synthesized via an eco-friendly approach that uses
Oxone® as the oxidant in the presence of a catalytic amount of iodine. This mild and …

A three-component [3+ 2]-cycloaddition/elimination cascade for the synthesis of spirooxindole-pyrrolizines

M Palomba, E De Monte, A Mambrini… - Organic & …, 2021 - pubs.rsc.org
A three-component synthesis of novel spirooxindole-tetrahydropyrrolizines from secondary α-
aminoacids, isatins and vinyl selenones has been disclosed. Products were formed in good …

Stereoselective construction of pyrazinoindoles and oxazinoindoles via ring-opening/pictet-spengler reaction of aziridines and epoxides with 3-methylindoles and …

IA Wani, S Das, S Mondal… - The Journal of Organic …, 2018 - ACS Publications
A highly efficient and stereoselective route to access 1, 3-disubstituted 1, 2, 3, 4-
tetrahydropyrazino [1, 2-a] indoles and 3, 4-dihydro-1H-[1, 4] oxazino [4, 3-a] indoles with …

A domino approach to pyrazino-indoles and pyrroles using vinyl selenones

M Palomba, L Sancineto, F Marini, C Santi, L Bagnoli - Tetrahedron, 2018 - Elsevier
Herein we disclose an efficient and flexible approach to biologically relevant 3, 4-
dihydropyrazino [1, 2-a] indol-1 (2H) ones and 3, 4-dihydropyrrolo [1, 2-a] pyrazin-1 (2H) …

Oxone‐Mediated Oxidation of Vinyl Selenides in Water

M Palomba, F Trappetti, L Bagnoli… - European Journal of …, 2018 - Wiley Online Library
A simple and practical procedure for the oxidation of vinyl selenides into the corresponding
selenones using Oxone in water at 60° C has been reported. Structurally diverse phenyl …

Vinylation of N-Heteroarenes through Addition/Elimination Reactions of Vinyl Selenones

M Palomba, IFC Dias, M Cocchioni, F Marini, C Santi… - Molecules, 2023 - mdpi.com
A new protocol for the synthesis of N-vinyl azoles using vinyl selenones and azoles in the
presence of potassium hydroxide was developed. This reaction proceeded under mild and …

Reductive Alkenylation of Ketimines via Hydride Transfer from Aldehydes

T Azaz, H Mourya, V Singh, B Ram… - The Journal of Organic …, 2022 - ACS Publications
The first direct N-heterocyclic carbene (NHC)-catalyzed preparation of allylic amines bearing
a quaternary center (α-tertiary amine) from isatin-derived ketimines in the presence of vinyl …

Chiral 1, 4-Oxazino [4, 3-a] indoles as a Challenging Scaffold: Syntheses and Properties

A Dupeux, V Michelet - Synthesis, 2023 - thieme-connect.com
In the last few decades, there has been an increasing interest in the development of new
syntheses of oxazinoindoles, a tricyclic backbone bearing an indole core structure fused …