Manganese (Mn) is an essential trace element with unique functions in the body; it acts as a
cofactor for many enzymes involved in energy metabolism, the endogenous antioxidant …

Manganese (Mn) is an essential trace element that is naturally found in the environment and
is necessary as a cofactor for many enzymes and is important in several physiological …

Behavioural disinhibition is a common feature of the syndromes associated with
frontotemporal lobar degeneration (FTLD). It is associated with high morbidity and lacks …

Introduction: The axial symptoms of Parkinson disease (PD) include difficulties with balance,
posture, speech, swallowing, and locomotion with freezing of gait, as well as axial rigidity …

Imbalances in glutamatergic (excitatory) and GABA (inhibitory) signalling within key brain
networks are thought to underlie many brain and mental health disorders, and for this …

Efficient action control is indispensable for goal-directed behaviour. Different theories have
stressed the importance of either attention or response selection sub-processes for action …

Parkinson's disease is characterized by bradykinesia, rigidity, and tremor. These symptoms
have been related to an increased gamma‐aminobutyric acid (GABA) ergic inhibitory drive …

Understanding the neurophysiological mechanisms that drive human behavior has been a
long-standing focus of cognitive neuroscience. One well-known neuro-metabolite involved …

Background Dysfunction of the primary motor cortex, participating in regulation of posture
and gait, is implicated in freezing of gait (FOG) in Parkinson's disease (PD). Objective The …

Abstract 1 H magnetic resonance spectroscopy (MRS) provides a powerful tool to measure
gamma-aminobutyric acid (GABA), the principle inhibitory neurotransmitter in the human …