Tobacco products present a deadly combination of nicotine addiction and carcinogen
exposure resulting in millions of cancer deaths per year worldwide. A plethora of smokeless …

Head and neck cancer (head and neck squamous cell carcinoma (HNSCC)) is a devastating
disease. Patients require intensive treatment that is often disfiguring and debilitating. Those …

The tobacco-specific N-nitrosamines 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone
(NNK) and N′-nitrosonornicotine (NNN) always occur together and exclusively in tobacco …

Since 2009, the FDA Center for Tobacco Products (CTP) has had the authority to regulate
the manufacturing, distribution, and marketing of tobacco products in order to reduce the …

Many harmful constituents are present in e-cigarettes at much lower levels than in cigarette
smoke, and the results of analysis of urinary biomarkers in e-cigarette users are consistent …

There is a paucity of evidence surrounding the potential detrimental effects of electronic
nicotine delivery systems (ENDS) for both systemic and oral health. The effects of …

Tobacco use is a major cause of preventable morbidity and mortality globally. Tobacco
products, including smokeless tobacco (ST), generally contain tobacco-specific N …

Tobacco-specific nitrosamines (TSNAs) are probably carcinogenic disinfection byproducts
eliciting health risk concerns. The determination and surveillance of TSNAs in water is still …

The oral cavity is usually the first part of a consumer's body exposed to the constituents of
tobacco products or their emissions. Consequently, the oral cavity is a frequent site for …

Tobacco-constituent biomarkers are metabolites of specific compounds present in tobacco
or tobacco smoke. Highly reliable analytic methods, based mainly on mass spectrometry …