Over the last two decades, the development of chemical biology and the need for more
defined protein conjugates have fostered active research on new bioconjugation …

Cell therapies represent a rapidly emerging class of new therapeutics. They are intended
and developed for the treatment of some of the most prevalent human diseases, including …

Gaussia luciferase (GLuc) is a small luciferase (18.2 kDa; 168 residues) and is thus
attracting much attention as a reporter protein, but the lack of structural information is …

Copepod luciferases—a family of small secretory proteins of 18.4–24.3 kD a, including a
signal peptide—are responsible for bright secreted bioluminescence of some marine …

In vivo imaging has enabled impressive advances in biological research, both preclinical
and clinical, and researchers have an arsenal of imaging methods available …

A mediator-free, non-enzymatic electrochemical biosensor was constructed by covalent
immobilization of a genetically engineered periplasmic glutamate binding protein onto gold …

Luciferases are widely used as sensitive reporters in various fields ranging from basic
biology to medical diagnosis, public health, and food inspection. Scientists have isolated …

Immunotherapy is a relatively new treatment regimen for cancer, and it is based on the
modulation of the immune system to battle cancer. Immunotherapies can be classified as …

Luciferases are widely used as reporters for gene expression and for sensitive detection
systems. The luciferase (GLuc) from the marine copepod Gaussia princeps, has gained …

Abstract Bioluminescence Resonance Energy Transfer (BRET) has been proven as a highly
sensitive optical transduction system for bio-imaging and a variety of analytical approaches …