In spite of the considerable achievements in the field of regenerative medicine in the past
several decades, osteochondral defect regeneration remains a challenging issue among …

Articular cartilage is commonly described as a tissue that is made of up to 80% water, is
devoid of blood vessels, nerves, and lymphatics, and is populated by only one cell type, the …

More than 32.5 million American adults suffer from osteoarthritis, and current treatments
including pain medicines and anti-inflammatory drugs only alleviate symptoms but do not …

Background: The role of evidence-based medicine in sports medicine and orthopaedic
surgery is rapidly growing. Systematic reviews and meta-analyses are also proliferating in …

Over the last 4 decades innovations in biomaterials and medical technology have had a
sustainable impact on the development of biopolymers, titanium/stainless steel and …

Background: The surfaces of the bones in the knee are covered with articular cartilage, a
rubber-like substance that is very smooth, allowing frictionless movement in the joint and …

Background Articular cartilage defects are a veritable therapeutic problem because
therapeutic options are very scarce. Due to the poor self-regeneration capacity of cartilage …

PURPOSE: The purposes of this study were (1) to analyze long-term outcomes in patients
who have undergone open or arthroscopic Bankart repair and (2) to evaluate study …

Background Autologous chondrocyte implantation (ACI) is an established and well-accepted
procedure for the treatment of localised full-thickness cartilage defects of the knee. Methods …

Current clinical approaches to treat articular cartilage degeneration provide only a limited
ability to regenerate tissue with long-term durability and functionality. In this application …