The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …

The human brain stands as an intricate organ, embodying a nexus of structure, function,
development, and diversity. This review delves into the multifaceted landscape of the brain …

During early development, the hindbrain is sub-divided into rhombomeres that underlie the
organisation of neurons and adjacent craniofacial tissues. A gene regulatory network of …

Hox genes play key roles in axial patterning and regulating the regional identity of cells and
tissues in a wide variety of animals from invertebrates to vertebrates. Nested domains of Hox …

From its long history in the field of embryology to its recent advances in genetics, Xenopus
has been an indispensable model for understanding the human brain. Foundational studies …

Hox transcription factors play fundamental roles during early patterning, but they are also
expressed continuously, from embryonic stages through adulthood, in the nervous system …

Interaction with the world around us requires extracting meaningful signals to guide
behavior. Each of the six mammalian senses (olfaction, vision, somatosensation, hearing …

The segregation of distinct cell populations to form sharp boundaries is crucial for stabilising
tissue organisation, for example during hindbrain segmentation in craniofacial development …

More than 25 years ago, the first literature records mentioned HOXA1 expression in human
breast cancer. A few years later, HOXA1 was confirmed as a proper oncogene in mammary …

Multicollinearity, characterized by significant co-expression patterns among genes, often
occurs in high-throughput expression data, potentially impacting the predictive model's …