Macrophages have a leading position in the tumor microenvironment (TME) which paves the
way to carcinogenesis. Initially, monocytes and macrophages are recruited to the sites …

Recent developments in the design of bifunctional and activatable photosensitizers
rejuvenate the aging field of photodynamic sensitization and photodynamic therapy. While …

Tumor-associated macrophages (TAMs) constitute the main population of immune cells
present in the ovarian tumor microenvironment. These cells are characterized by high …

Mononuclear phagocyte plasticity includes the expression of functions related to the
resolution of inflammation, tissue repair and remodelling, particularly when these cells are …

In epithelial cancers, cells must invade through basement membranes (BMs) to metastasize.
The BM, a thin layer of extracellular matrix underlying epithelial and endothelial tissues, is …

Myeloid cells are the most abundant nucleated haematopoietic cells in the human body and
are a collection of distinct cell populations with many diverse functions. The three groups of …

Tumor-associated macrophages (TAMs) can influence ovarian cancer growth, migration,
and metastasis, but the detailed mechanisms underlying ovarian cancer metastasis remain …

BACKGROUND Predicting survival is uniquely difficult in patients with pancreatic cancer
who receive chemotherapy. The authors developed a systemic inflammation response index …

Tumor-associated macrophages (TAMs) can have protumor properties, including
suppressing immune responses, promoting vascularization and, consequently, augmenting …

The observation that a subset of cancer patients show evidence for spontaneous CD8+ T
cell priming against tumor-associated antigens has generated renewed interest in the innate …