HIV infection has transitioned from an acute, fatal disease to a chronic one managed by
antiretroviral therapy. Thus, the aging population of people living with HIV (PLWH) continues …

The human immunodeficiency virus type I (HIV-1) has developed several strategies to
condition the host environment to promote viral replication and spread. Viral proteins have …

The different members of the vascular endothelial growth factor (VEGF) family act as key
regulators of endothelial cell function controlling vasculogenesis, angiogenesis, vascular …

Symptoms of T cell hyperactivation shape the course and outcome of HIV-1 infection, but the
mechanism (s) underlying this chronic immune activation are not well understood. We find …

Kaposi's sarcoma (KS) is an angioproliferative disease occurring in 4 clinic-epidemiologic
forms. Although the AIDS-associated KS (AIDS-KS) is the most aggressive, all forms of KS …

Nuclear factor (NF)-κB is a master regulator of pro-inflammatory genes and is upregulated in
human immunodeficiency virus 1 (HIV-1) infection. Mechanisms underlying the NF-κB …

Human endogenous retroviruses (HERVs) make up 8% of the human genome. The
expression of HERV-K (HML-2), the family of HERVs that most recently entered the genome …

A recombinant Tat protein was used to investigate the molecular mechanisms of
transcriptional activation of the human immunodeficiency virus type 1 long terminal repeat …

▪ Abstract Intracellular antibodies (intrabodies) represent a new class of neutralizing
molecules with a potential use in gene therapy. Intrabodies are engineered single-chain …

Human immunodeficiency virus type 1 (HIV-1) infection is associated with severe psoriasis,
B cell lymphoma, and Kaposi's sarcoma. A deregulated production of interleukin-6 (IL6) has …