Cardiovascular disease is the leading cause of death worldwide, with this trend predicted to
continue for the foreseeable future. Common disorders are associated with the stenosis or …

Since the emergence of regenerative medicine and tissue engineering more than half a
century ago, one obstacle has persisted: the in vitro creation of large-scale vascular tissue (> …

There is a growing demand for off-the-shelf tissue engineered vascular grafts (TEVGs) for
the replacement or bypass of damaged arteries in various cardiovascular diseases …

Occlusive arterial disease, including coronary heart disease (CHD) and peripheral arterial
disease (PAD), is the main cause of death, with an annual mortality incidence predicted to …

As a type of elastomeric polymers, non-degradable polyurethanes (PUs) have a long history
of being used in clinics, whereas biodegradable PUs have been developed in recent …

From microscaled capillaries to millimeter‐sized vessels, human vasculature spans multiple
scales and cell types. The convergence of bioengineering, materials science, and stem cell …

Cardiovascular tissue engineering aims to find solutions for the suboptimal regeneration of
heart valves, arteries and myocardium by creating 'living'tissue replacements outside (in …

Polymeric nanofibers have potential as tissue engineering scaffolds, as they mimic the
nanoscale properties and structural characteristics of native extracellular matrix (ECM) …

Blood vessels transport blood to deliver oxygen and nutrients. Vascular diseases such as
atherosclerosis may result in obstruction of blood vessels and tissue ischemia. These …

There is great clinical demand for synthetic vascular grafts with improved long-term efficacy.
The ideal vascular conduit is easily implanted, nonthrombogenic, biocompatible, resists …