Cardiac and skeletal striated muscles are intricately designed machines responsible for
muscle contraction. Coordination of the basic contractile unit, the sarcomere, and the …

The sarcomere is the basic contractile unit of striated muscle and is a highly ordered protein
complex with the actin and myosin filaments at its core. Assembling the sarcomere …

Tropomodulins are a family of four proteins (Tmods 1–4) that cap the pointed ends of actin
filaments in actin cytoskeletal structures in a developmentally regulated and tissue‐specific …

In striated muscle, the actin cytoskeleton is differentiated into myofibrils. Actin and myosin
filaments are organized in sarcomeres and specialized for producing contractile forces …

Cytoskeletal structures characterized by actin filaments with uniform lengths, including the
thin filaments of striated muscles and the spectrin-based membrane skeleton, use barbed …

Leiomodin 2 (Lmod2) is an actin-binding protein that has been implicated in the regulation
of striated muscle thin filament assembly; its physiological function has yet to be studied. We …

Smooth muscle cell (SMC) differentiation is defined largely by a number of cell-restricted
genes governed directly by the serum response factor (SRF)/myocardin (MYOCD) …

Regulation of actin filament assembly is essential for efficient contractile activity in striated
muscle. Leiomodin is an actin-binding protein and homolog of the pointed-end capping …

The actin (thin) filaments in striated muscle are highly regulated and precisely specified in
length to optimally overlap with the myosin (thick) filaments for efficient myofibril contraction …

The mammalian erythrocyte, or red blood cell (RBC), is a unique experiment of nature: a cell
with no intracellular organelles, nucleus or transcellular cytoskeleton, and a plasma …