BACKGROUND ICSI is currently the most commonly used assisted reproductive technology,
accounting for 70–80% of the cycles performed. This extensive use, even excessive, is partly …

Sperm pathology is presented as the discipline of characterizing structural and functional
deficiencies in abnormal spermatozoa. This concept complements that of sperm morphology …

Globozoospermia is a rare (incidence< 0.1%) but severe disorder in male infertility. Total
globozoospermia is diagnosed by the presence of 100% round-headed spermatozoa …

Abstract From October 1992 to December 1994, 2732 cycles of treatment by
intracytoplasmic sperm injection (ICSI) were carried out in couples mainly with severe male …

The aim of this study was to examine the relationship between different preincubation
periods of oocytes and the outcome of intracytoplasmic sperm injection (ICSI). We analysed …

Intracytoplasmic sperm injection (ICSI) has become the method of choice to overcome male
infertility when all other forms of assisted fertilization have failed. Animals in which ICSI has …

Notwithstanding the broad success of in vitro fertilization (IVF), a failure to achieve
fertilization still plagues a substantial group of patients, with sperm abnormalities the main …

Objective To describe the novel micromanipulation technique known as intracytoplasmic
sperm injection (ICSI), which has been applied successfully to treat male factor infertility …

Intracytoplasmic sperm injection (ICSI) is the most effective assisted reproductive procedure
enabling fertilization in severe forms of male factor indications and male gamete dysfunction …

We recently identified the DPY19L2 gene as the main genetic cause of human
globozoospermia (70%) and described that Dpy19l2 knockout (KO) mice faithfully reproduce …