Epigenetic mechanism involved in the HBV/HCV-related hepatocellular carcinoma tumorigenesis

L Rongrui, H Na, L Zongfang, J Fanpu… - Current …, 2014 - ingentaconnect.com
Hepatitis B virus (HBV) and hepatitis C virus (HCV) infection were known to be risk factors
for HCC, they were suspected to promote its development by eliciting epigenetic changes …

Hepatocellular carcinoma and other malignancies in autoimmune hepatitis

AJ Czaja - Digestive diseases and sciences, 2013 - Springer
Hepatocellular carcinoma and extrahepatic malignancies can complicate the course of
autoimmune hepatitis, and these occurrences may increase in frequency as the survival of …

[HTML][HTML] MiR-219-5p inhibits hepatocellular carcinoma cell proliferation by targeting glypican-3

N Huang, J Lin, J Ruan, N Su, R Qing, F Liu, B He, C Lv… - FEBS letters, 2012 - Elsevier
MicroRNAs (miRNAs) have been linked to the molecular pathogenesis of many cancers. In
this study, we found that miR-219-5p was significantly downregulated in 83 HCC tissues and …

MiR-141 suppresses the migration and invasion of HCC cells by targeting Tiam1

Y Liu, Y Ding, J Huang, S Wang, W Ni, J Guan, Q Li… - PloS one, 2014 - journals.plos.org
Background We have demonstrated that T lymphoma invasion and metastasis 1 (Tiam1)
gene is associated with the poor prognosis of patients with hepatocellular carcinoma (HCC) …

miR-144 suppresses the proliferation and metastasis of hepatocellular carcinoma by targeting E2F3

T Cao, H Li, Y Hu, D Ma, X Cai - Tumor Biology, 2014 - Springer
MicroRNAs (miRNAs) play essential roles in the progression of hepatocellular carcinoma
(HCC). miR-144 acts as a tumor suppressor in some malignancies, while its role in HCC is …

Methylation‐mediated repression of micro RNA 129‐2 enhances oncogenic SOX 4 expression in HCC

X Chen, L Zhang, T Zhang, M Hao, X Zhang… - Liver …, 2013 - Wiley Online Library
Abstract Background & Aims Aberration of miR‐129‐2 has been linked to a variety of human
tumours. However, whether miR‐129‐2 is involved in hepatocarcinogenesis remains …

Upregulation of microRNA-372 associates with tumor progression and prognosis in hepatocellular carcinoma

H Gu, X Guo, L Zou, H Zhu, J Zhang - Molecular and cellular biochemistry, 2013 - Springer
Abstract MicroRNA-372 (miR-372) has been demonstrated to play a crucial role in cellular
proliferation and apoptosis of cancer cells. However, its effects in hepatocellular carcinoma …

miR‑145‑5p reduces proliferation and migration of hepatocellular carcinoma by targeting KLF5

H Liang, H Sun, J Yang, C Yi - Molecular Medicine …, 2018 - spandidos-publications.com
MicroRNAs (miRs) are important in hepatocellular carcinoma (HCC) progression. miR‑145‑
5p acts as a tumor suppressor in certain malignancies, however, its role in HCC remains …

MicroRNA‐219‐5p Promotes Tumor Growth and Metastasis of Hepatocellular Carcinoma by Regulating Cadherin 1

J Yang, YY Sheng, JW Wei, XM Gao… - BioMed research …, 2018 - Wiley Online Library
MicroRNAs play significant roles in the development of cancer and may serve as promising
therapeutic targets. In our previous work, miR‐219‐5p was identified as one of the important …

Low mir-372 expression correlates with poor prognosis and tumor metastasis in hepatocellular carcinoma

G Wu, Y Wang, X Lu, H He, H Liu, X Meng, S Xia… - BMC cancer, 2015 - Springer
Background Recent studies have shown that miR-372 plays important roles in
hepatocellular carcinoma (HCC) progression. However, results have been conflicting …