In vitro and in vivo biological activities of azulene derivatives with potential applications in medicine

P Bakun, B Czarczynska-Goslinska, T Goslinski… - Medicinal Chemistry …, 2021 - Springer
Azulene is an aromatic hydrocarbon that possesses a unique chemical structure and
interesting biological properties. Azulene derivatives, including guaiazulene or …

Azulene—A bright core for sensing and imaging

LC Murfin, SE Lewis - Molecules, 2021 - mdpi.com
Azulene is a hydrocarbon isomer of naphthalene known for its unusual colour and
fluorescence properties. Through the harnessing of these properties, the literature has been …

Azulene-derived fluorescent probe for bioimaging: detection of reactive oxygen and nitrogen species by two-photon microscopy

LC Murfin, M Weber, SJ Park, WT Kim… - Journal of the …, 2019 - ACS Publications
Two-photon fluorescence microscopy has become an indispensable technique for cellular
imaging. Whereas most two-photon fluorescent probes rely on well-known fluorophores …

Azulene-based fluorescent chemosensor for adenosine diphosphate

CM López-Alled, SJ Park, DJ Lee, LC Murfin… - Chemical …, 2021 - pubs.rsc.org
AzuFluor® 435-DPA-Zn, an azulene fluorophore bearing two zinc (II)-dipicolylamine
receptor motifs, exhibits fluorescence enhancement in the presence of adenosine …

Colorimetric detection of Hg 2+ with an azulene-containing chemodosimeter via dithioacetal hydrolysis

CM López-Alled, LC Murfin, G Kociok-Köhn, TD James… - Analyst, 2020 - pubs.rsc.org
Azulene is a bicyclic aromatic chromophore that absorbs in the visible region. Its absorption
maximum undergoes a hypsochromic shift if a conjugated electron-withdrawing group is …

Recent Advances in the Functionalization of Azulene Through Pd‐Catalyzed Cross‐Coupling Reactions

AHM Elwahy, IA Abdelhamid, MR Shaaban - ChemistrySelect, 2021 - Wiley Online Library
Azulene derivatives have important physical and physicochemical features, as well as
advantageous biological qualities. The metal‐catalyzed processes have proven to be a …

A simple, azulene-based colorimetric probe for the detection of nitrite in water

LC Murfin, CM López-Alled, AC Sedgwick… - Frontiers of Chemical …, 2020 - Springer
We describe the synthesis and evaluation of an azulene-based chemodosimeter for nitrite.
The probe was found to undergo two distinct color changes upon introduction of aqueous …

Electrochemical System for Field Control of Hg2+ Concentration in Wastewater Samples

AG Tenea, C Dinu, GO Buica, GG Vasile - Sensors, 2023 - mdpi.com
The paper presents the validation of an electrochemical procedure for on-site Hg2+ ions
determination in wastewater samples using a modified carbon screen-printed electrode …

A colorimetric chemosensor based on a Nozoe azulene that detects fluoride in aqueous/alcoholic media

LC Murfin, K Chiang, GT Williams, CL Lyall… - Frontiers in …, 2020 - frontiersin.org
Colorimetry is an advantageous method for detecting fluoride in drinking water in a resource-
limited context, eg, in parts of the developing world where excess fluoride intake leads to …

Azulenes with aryl substituents bearing pentafluorosulfanyl groups: synthesis, spectroscopic and halochromic properties

SJ Webster, CM López-Alled, X Liang… - New Journal of …, 2019 - pubs.rsc.org
Four regioisomeric azulenes bearing pentafluorosulfanylphenyl substituents have been
prepared and characterised by various spectroscopic techniques. The absorption spectra …