Cancer stem cells (CSCs) play a central role in tumor progression, recurrence, and
resistance to conventional therapies, making them a critical focus in oncology research. This …

Advanced Therapy Medicinal Products (ATMPs) are a novel class of biological therapeutics
that utilise ground-breaking clinical interventions to prevent and treat life-threatening …

Cancer stem cells (CSCs), which represent the root cause of resistance to conventional
treatments, recurrence, and metastasis, constitute the critical point of failure in cancer …

In recent decades, the mathematical modeling of infectious diseases, real-world problems,
non-linear dynamical complex systems, etc., has increased significantly. According to World …

Background: Cancer cells are intimately intertwined with tumor microenvironment (TME),
fostering a symbiotic relationship propelling cancer progression. However, the interaction …

This paper evaluates the nonlinear dynamics of a melanoma cancer model through the
iterative technique of finding compact invariant sets (LMCIS). The objective is to discover …

The stem cell hypothesis suggests that there is a small group of malignant cells, the cancer
stem cells, that initiate the development of tumors, encourage its growth, and may even be …

In previous work, we presented a model that integrates cancer cell differentiation and
immunotherapy, analysing a particular therapy against cancer stem cells by cytotoxic cell …

In the present investigation, a stochastic tumor growth model is presented based on the
Morse potential. The solution of the Fokker–Planck equation is used to study the growth rate …

In this paper, a tumour-immune model with pulsed treatment of different frequency is
proposed. The globally attractive conditions of the tumour-free periodic solution are …