Family of melanocortin receptor (MCR) genes in mammals—mutations, polymorphisms and phenotypic effects

M Switonski, M Mankowska, S Salamon - Journal of applied genetics, 2013 - Springer
The melanocortin receptor gene family consists of five single-exon members, which are
located on autosomes. Three genes (MC2R, MC4R and MC5R) are syntenic in the human …

Genetic marker discovery in complex traits: a field example on fat content and composition in pigs

RN Pena, R Ros-Freixedes, M Tor, J Estany - International Journal of …, 2016 - mdpi.com
Among the large number of attributes that define pork quality, fat content and composition
have attracted the attention of breeders in the recent years due to their interaction with …

Genome-Wide Association Study Singles Out SCD and LEPR as the Two Main Loci Influencing Intramuscular Fat Content and Fatty Acid Composition in Duroc Pigs

R Ros-Freixedes, S Gol, RN Pena, M Tor… - PLoS …, 2016 - journals.plos.org
Intramuscular fat (IMF) content and fatty acid composition affect the organoleptic quality and
nutritional value of pork. A genome-wide association study was performed on 138 Duroc …

Effects of melanocortin-4 receptor gene on growth and meat traits in pigs raised in Russia.

A Klimenko, A Usatov, L Getmantseva, Y Kolosov… - 2014 - cabidigitallibrary.org
Abstract The Melanocortin-4 Receptor (MC4R), a G-protein coupled receptor, is implicated
in mediating the effect of leptin on food intake and energy balance. A previous candidate …

Identification of genes related to intramuscular fat independent of backfat thickness in Duroc pigs using single‐step genome‐wide association

Z Zhang, Z Zhang, FO Oyelami, H Sun, Z Xu… - Animal …, 2021 - Wiley Online Library
Intramuscular fat (IMF) is an important meat‐quality trait of pigs, which influences pork's
shearing force, hydraulics, tenderness and juicy flavor. However, to achieve a higher …

Preadipocyte and adipose tissue differentiation in meat animals: influence of species and anatomical location

GJ Hausman, U Basu, S Wei… - Annu. Rev. Anim …, 2014 - annualreviews.org
Early in porcine adipose tissue development, the stromal-vascular (SV) elements control
and dictate the extent of adipogenesis in a depot-dependent manner. The vasculature and …

Integrated analysis of lncRNA and mRNA in subcutaneous adipose tissue of Ningxiang pig

Y Gong, J He, B Li, Y Xiao, Q Zeng, K Xu, Y Duan, J He… - Biology, 2021 - mdpi.com
Simple Summary This study shows the transcription profiles and the functional network in
lncRNA and mRNA in the subcutaneous adipose tissue of Ningxiang piglets in four stages of …

[HTML][HTML] Candidate SNPs for meat quality and carcass composition in free-range Iberian pigs

P Palma-Granados, M Muñoz, MA Delgado-Gutierrez… - Meat Science, 2024 - Elsevier
Several genetic markers, previously associated with meat quality traits, have been proposed
to be included in Iberian pig breeding programs. However, before being implemented …

Genetics of adiposity in large animal models for human obesity—studies on pigs and dogs

M Stachowiak, I Szczerbal, M Switonski - Progress in molecular biology …, 2016 - Elsevier
The role of domestic mammals in the development of human biomedical sciences has been
widely documented. Among these model species the pig and dog are of special importance …

Possible effects of the MC4R Asp298Asn polymorphism on pig production traits under ad libitum versus restricted feeding

J Calta, K Zadinová, J Čítek… - Journal of Animal …, 2023 - Wiley Online Library
Abstract The missense mutation Asp298Asn in the melanocortin 4 receptor (MC4R) is
associated with daily gain or fatness in pigs (Sus scrofa domesticus). However, to the best of …