Chemically modified and conjugated antimicrobial peptides against superbugs

W Li, F Separovic, NM O'Brien-Simpson… - Chemical Society …, 2021 - pubs.rsc.org
Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050,
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …

Antimicrobial host defence peptides: functions and clinical potential

N Mookherjee, MA Anderson, HP Haagsman… - Nature reviews Drug …, 2020 - nature.com
Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally
occurring peptides that can combat infections through their direct microbicidal properties …

Strategies employed in the design of antimicrobial peptides with enhanced proteolytic stability

Z Lai, X Yuan, H Chen, Y Zhu, N Dong, A Shan - Biotechnology Advances, 2022 - Elsevier
Due to the alarming developing rate of multidrug-resistant bacterial pathogens, the
development and modification of antimicrobial peptides (AMPs) are unprecedentedly active …

Mini review on antimicrobial peptides, sources, mechanism and recent applications

JK Boparai, PK Sharma - Protein and peptide letters, 2020 - ingentaconnect.com
Antimicrobial peptides in recent years have gained increased interest among scientists,
health professionals and the pharmaceutical companies owing to their therapeutic potential …

Antimicrobial peptides: mechanism of action, activity and clinical potential

QY Zhang, ZB Yan, YM Meng, XY Hong, G Shao… - Military Medical …, 2021 - Springer
The management of bacterial infections is becoming a major clinical challenge due to the
rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome …

The vast structural diversity of antimicrobial peptides

J Koehbach, DJ Craik - Trends in pharmacological sciences, 2019 - cell.com
Antimicrobial peptides (AMPs) occur in all kingdoms of life and are integral to host defense.
They have diverse structures and target a variety of organisms, both by nonspecific …

Antimicrobial mechanisms and clinical application prospects of antimicrobial peptides

X Li, S Zuo, B Wang, K Zhang, Y Wang - Molecules, 2022 - mdpi.com
Antimicrobial peptides are a type of small-molecule peptide that widely exist in nature and
are components of the innate immunity of almost all living things. They play an important role …

The multifaceted roles of proline in cell behavior

EJ Patriarca, F Cermola, C D'Aniello, A Fico… - Frontiers in cell and …, 2021 - frontiersin.org
Herein, we review the multifaceted roles of proline in cell biology. This peculiar cyclic imino
acid is:(i) A main precursor of extracellular collagens (the most abundant human proteins) …

Antimicrobial peptides and their application in food packaging

Y Liu, DE Sameen, S Ahmed, J Dai, W Qin - Trends in Food Science & …, 2021 - Elsevier
Background Food safety and spoilage prevention are the main concerns in the food
packaging industry. Microbial contamination is one of the biggest causes of food …

Tryptophan-rich and proline-rich antimicrobial peptides

AK Mishra, J Choi, E Moon, KH Baek - Molecules, 2018 - mdpi.com
Due to the increasing emergence of drug-resistant pathogenic microorganisms, there is a
world-wide quest to develop new-generation antibiotics. Antimicrobial peptides (AMPs) are …