Testosterone and obesity

DM Kelly, TH Jones - Obesity Reviews, 2015 - Wiley Online Library
Testosterone is a key hormone in the pathology of metabolic diseases such as obesity. Low
testosterone levels are associated with increased fat mass (particularly central adiposity) …

Paediatric and adult-onset male hypogonadism

A Salonia, G Rastrelli, G Hackett… - Nature reviews Disease …, 2019 - nature.com
The hypothalamic–pituitary–gonadal axis is of relevance in many processes related to the
development, maturation and ageing of the male. Through this axis, a cascade of …

Mechanisms in endocrinology: Vitamin D and fertility: a systematic review

E Lerchbaum… - European journal of …, 2012 - academic.oup.com
Background Vitamin D has been well-known for its function in maintaining calcium and
phosphorus homeostasis and promoting bone mineralization. There is some evidence that …

Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome

A Dunaif, KR Segal, W Futterweit, A Dobrjansky - Diabetes, 1989 - Am Diabetes Assoc
Hyperinsulinemia secondary to a poorly characterized disorder of insulin action is a feature
of the polycystic ovary syndrome (PCO). However, controversy exists as to whether insulin …

Gender differences in insulin resistance, body composition, and energy balance

EB Geer, W Shen - Gender medicine, 2009 - Elsevier
Background: Men and women differ substantially in regard to degrees of insulin resistance,
body composition, and energy balance. Adipose tissue distribution, in particular the …

Novel insights in SHBG regulation and clinical implications

R Simó, C Sáez-López, A Barbosa-Desongles… - Trends in Endocrinology …, 2015 - cell.com
Sex hormone-binding globulin (SHBG) is produced and secreted by the liver into the
bloodstream where it binds sex steroids and regulates their bioavailability. Traditionally …

Male hypogonadism

S Basaria - The Lancet, 2014 - thelancet.com
Male hypogonadism is a clinical syndrome that results from failure to produce physiological
concentrations of testosterone, normal amounts of sperm, or both. Hypogonadism may arise …

Lowered testosterone in male obesity: mechanisms, morbidity and management

MNT Fui, P Dupuis, M Grossmann - Asian journal of andrology, 2014 - journals.lww.com
With increasing modernization and urbanization of Asia, much of the future focus of the
obesity epidemic will be in the Asian region. Low testosterone levels are frequently …

Hormonal and metabolic changes of aging and the influence of lifestyle modifications

MW Pataky, WF Young, KS Nair - Mayo Clinic Proceedings, 2021 - Elsevier
Increased life expectancy combined with the aging baby boomer generation has resulted in
an unprecedented global expansion of the elderly population. The growing population of …

Obesity and male infertility

BE Kahn, RE Brannigan - Current opinion in urology, 2017 - journals.lww.com
Obesity and male infertility : Current Opinion in Urology Obesity and male infertility : Current
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