Our ability to detect, image, and quantify nanoscopic objects and molecules with visible light
has undergone dramatic improvements over the past few decades. While fluorescence has …

Developments of optical detection and spectroscopy methods for single nano-objects are
key advances for applications and fundamental understanding of the novel properties …

Signal processing is of critical importance for various science and technology fields. Analog
optical processing can provide an effective solution to perform large-scale and real-time …

(60) Provisional application No. 60/547,611, filed on Feb. 5,405,783 A 4/1995 Pirrung et al.
24, 2004, provisional application No. 60/546,277. 5,409,811 A 4/1995 Tabor et al. filed on …

The present invention relates to a novel method for analyzing nucleic acid sequences based
on real-time detection of DNA poly-merase-catalyzed incorporation of each of the four …

US7501245B2 - Methods and apparatuses for analyzing polynucleotide sequences - Google
Patents US7501245B2 - Methods and apparatuses for analyzing polynucleotide sequences …

Molecular motors such as kinesin, myosin, and F 1-ATPase are responsible for many
important cellular processes. These motor proteins exhibit nanometer-scale, stepwise …

US7897345B2 - Short cycle methods for sequencing polynucleotides - Google Patents
US7897345B2 - Short cycle methods for sequencing polynucleotides - Google Patents Short …

A device is described having a first surface having a plurality of first areas and a second
surface having a plurality of second areas. The first surface and the second surface are …

The study of cellular processes such as organelle transport often demands particle tracking
with microsecond time‐resolution and nanometer spatial precision, posing significant …