[HTML][HTML] Thin films as an emerging platform for drug delivery

S Karki, H Kim, SJ Na, D Shin, K Jo, J Lee - Asian journal of pharmaceutical …, 2016 - Elsevier
Pharmaceutical scientists throughout the world are trying to explore thin films as a novel
drug delivery tool. Thin films have been identified as an alternative approach to conventional …

Nanosuspensions in ophthalmology: Overcoming challenges and enhancing drug delivery for eye diseases

S Fathi-Karkan, NA Ramsheh, H Arkaban… - International Journal of …, 2024 - Elsevier
This review article provides a comprehensive overview of the advancements in using
nanosuspensions for controlled drug delivery in ophthalmology. It highlights the significance …

Liposome incorporated ion sensitive in situ gels for opthalmic delivery of timolol maleate

S Yu, QM Wang, X Wang, D Liu, W Zhang, T Ye… - International journal of …, 2015 - Elsevier
This study was aimed to design a liposomal based ion-sensitive in situ ophthalmic delivery
system of timolol maleate (TM). The TM liposome was produced by the reverse evaporation …

In vitro and ex vivo corneal penetration and absorption models

P Agarwal, ID Rupenthal - Drug delivery and translational research, 2016 - Springer
Topical drug administration is the preferred route of drug delivery to the eye despite the poor
bioavailability. To develop more efficient drug carriers, reliable in vitro or ex vivo models are …

[HTML][HTML] Development and optimization of vildagliptin solid lipid nanoparticles loaded ocuserts for controlled ocular delivery: A promising approach towards treating …

MMA Elsayed, A Elsayed, MA Fouad… - International Journal of …, 2024 - Elsevier
Diabetes mellitus (DM) is the most prevalent cause of diabetic retinopathy (DRP). DRP has
been recognized for a long time as a microvascular disease. Many drugs were used to treat …

Determination of permeability coefficients of ophthalmic drugs through different layers of porcine, rabbit and bovine eyes

C Loch, S Zakelj, A Kristl, S Nagel, R Guthoff… - European journal of …, 2012 - Elsevier
To treat ophthalmic diseases like glaucoma or inflammatory disorders topically applied
ophthalmic formulations such as eye drops are usually used. In addition, novel ophthalmic …

Optimization of Thermoreversible In Situ Nasal Gel of Timolol Maleate

S Jagdale, N Shewale, BS Kuchekar - Scientifica, 2016 - Wiley Online Library
Nasal route had shown better systemic bioavailability due to its large surface area, porous
endothelial membrane, high total blood flow, and avoidance of first‐pass metabolism …

Randomized clinical trial of the efficacy and safety of preservative-free tafluprost and timolol in patients with open-angle glaucoma or ocular hypertension

A Chabi, R Varma, JC Tsai, R Lupinacci… - American journal of …, 2012 - Elsevier
PURPOSE: To compare the efficacy and safety of tafluprost, a preservative-free (PF)
prostaglandin analogue, with PF timolol in patients with open-angle glaucoma or ocular …

Sustained release timolol maleate loaded ocusert based on biopolymer composite

RV Nair, S Shefrin, A Suresh, KR Anoop… - International Journal of …, 2018 - Elsevier
In the present investigation, the effect of timolol maleate loaded ocuserts was studied as an
alternative for conventional anti-glaucoma formulation. Ocuserts were prepared using …

Measurements and Correlation of Timolol Maleate Solubility in Biobased Neat and Binary Solvent Mixtures

L Zimmermann, HL Lee, A Koishybay… - Journal of Chemical & …, 2024 - ACS Publications
A crucial factor in the development of sustainable crystallization processes is the use of
biobased solvents, which, in turn, necessitates a comprehensive understanding of the …