Contextualizing context for synthetic biology–identifying causes of failure of synthetic biological systems
S Cardinale, AP Arkin - Biotechnology journal, 2012 - Wiley Online Library
Despite the efforts that bioengineers have exerted in designing and constructing biological
processes that function according to a predetermined set of rules, their operation remains …
processes that function according to a predetermined set of rules, their operation remains …
Macromolecular inhibition of quorum sensing: enzymes, antibodies, and beyond
This review article focuses on quenching of bacterial quorum sensing (QS) signaling by
macromolecules. Although various research efforts have led to the design and identification …
macromolecules. Although various research efforts have led to the design and identification …
Dynamic regulation of N-acyl-homoserine lactone production and degradation in Pseudomonas putida IsoF
The biocontrol strain Pseudomonas putida IsoF, which was isolated from a tomato
rhizosphere, is a known N-acyl-homoserine lactone (AHL) producer with only one LuxI/LuxR …
rhizosphere, is a known N-acyl-homoserine lactone (AHL) producer with only one LuxI/LuxR …
Acylase‐containing polyurethane coatings with anti‐biofilm activity
N Grover, JG Plaks, SR Summers… - Biotechnology and …, 2016 - Wiley Online Library
Due to the prevalence of biofilm‐related infections, which are mediated by bacterial quorum
sensing, there is a critical need for materials and coatings that resist biofilm formation. We …
sensing, there is a critical need for materials and coatings that resist biofilm formation. We …
Sinorhizobium meliloti, a bacterium lacking the autoinducer‐2 (AI‐2) synthase, responds to AI‐2 supplied by other bacteria
CS Pereira, JR McAuley, ME Taga… - Molecular …, 2008 - Wiley Online Library
Many bacterial species respond to the quorum‐sensing signal autoinducer‐2 (AI‐2) by
regulating different niche‐specific genes. Here, we show that Sinorhizobium meliloti, a plant …
regulating different niche‐specific genes. Here, we show that Sinorhizobium meliloti, a plant …
Vanadium bromoperoxidase from Delisea pulchra: enzyme-catalyzed formation of bromofuranone and attendant disruption of quorum sensing
M Sandy, JN Carter-Franklin, JD Martin… - Chemical …, 2011 - pubs.rsc.org
Vanadium bromoperoxidase was isolated and cloned from the marine red alga Delisea
pulchra. This enzyme catalyzes the bromolactonization of 4-pentynoic acid forming 5E …
pulchra. This enzyme catalyzes the bromolactonization of 4-pentynoic acid forming 5E …
Engineering multicellular systems by cell–cell communication
Synthetic biology encompasses the design of new biological parts and systems as well as
the modulation of existing biological networks to generate novel functions. In recent years …
the modulation of existing biological networks to generate novel functions. In recent years …
Microbial metabolism of quorum-sensing molecules acyl-homoserine lactones, γ-heptalactone and other lactones
M Safari, R Amache, E Esmaeilishirazifard… - Applied microbiology …, 2014 - Springer
The cell-to-cell communication of microorganisms is known to be via exertion of certain
chemical compounds (signal molecules) and is referred to as quorum sensing (QS). QS …
chemical compounds (signal molecules) and is referred to as quorum sensing (QS). QS …
Traveling waves in response to a diffusing quorum sensing signal in spatially-extended bacterial colonies
JB Langebrake, GE Dilanji, SJ Hagen… - Journal of theoretical …, 2014 - Elsevier
In the behavior known as quorum sensing (QS), bacteria release diffusible signal molecules
known as autoinducers, which by accumulating in the environment induce population-wide …
known as autoinducers, which by accumulating in the environment induce population-wide …