[HTML][HTML] Supramolecular engineering of hydrogels for drug delivery

S Bernhard, MW Tibbitt - Advanced Drug Delivery Reviews, 2021 - Elsevier
Supramolecular binding motifs are increasingly employed in the design of biomaterials. The
ability to rationally engineer specific yet reversible associations into polymer networks with …

Enzymatic noncovalent synthesis

H He, W Tan, J Guo, M Yi, AN Shy, B Xu - Chemical reviews, 2020 - ACS Publications
Enzymatic reactions and noncovalent (ie, supramolecular) interactions are two fundamental
nongenetic attributes of life. Enzymatic noncovalent synthesis (ENS) refers to a process …

Supramolecular hydrogelators and hydrogels: from soft matter to molecular biomaterials

X Du, J Zhou, J Shi, B Xu - Chemical reviews, 2015 - ACS Publications
In this review we intend to provide a relatively comprehensive summary of the work of
supramolecular hydrogelators after 2004 and to put emphasis particularly on the …

Nanoscale self-assembly for therapeutic delivery

S Yadav, AK Sharma, P Kumar - Frontiers in Bioengineering and …, 2020 - frontiersin.org
Self-assembly is the process of association of individual units of a material into highly
arranged/ordered structures/patterns. It imparts unique properties to both inorganic and …

Self-assembled peptide-based nanostructures: Smart nanomaterials toward targeted drug delivery

N Habibi, N Kamaly, A Memic, H Shafiee - Nano today, 2016 - Elsevier
Self-assembly of peptides can yield an array of well-defined nanostructures that are highly
attractive nanomaterials for many biomedical applications such as drug delivery. Some of …

Functional π-gelators and their applications

SS Babu, VK Praveen, A Ajayaghosh - Chemical reviews, 2014 - ACS Publications
Supramolecular chemistry originally defined by Lehn as “chemistry beyond molecules”
exploits noncovalent interactions between molecules to form 1D, 2D, and 3D …

Peptide–drug conjugates as effective prodrug strategies for targeted delivery

Y Wang, AG Cheetham, G Angacian, H Su, L Xie… - Advanced drug delivery …, 2017 - Elsevier
Peptide–drug conjugates (PDCs) represent an important class of therapeutic agents that
combine one or more drug molecules with a short peptide through a biodegradable linker …

Self-assembling prodrugs

AG Cheetham, RW Chakroun, W Ma… - Chemical Society Reviews, 2017 - pubs.rsc.org
Covalent modification of therapeutic compounds is a clinically proven strategy to devise
prodrugs with enhanced treatment efficacies. This prodrug strategy relies on the modified …

Stimuli-responsive supramolecular polymeric materials

X Yan, F Wang, B Zheng, F Huang - Chemical Society Reviews, 2012 - pubs.rsc.org
Supramolecular materials, dynamic materials by nature, are defined as materials whose
components are bridged via reversible connections and undergo spontaneous and …

Functional supramolecular polymers for biomedical applications

R Dong, Y Zhou, X Huang, X Zhu, Y Lu… - Advanced …, 2015 - Wiley Online Library
As a novel class of dynamic and non‐covalent polymers, supramolecular polymers not only
display specific structural and physicochemical properties, but also have the ability to …